In this work to determine the effects of metals exposure of Oreochromis niloticus on erythrocyte antioxidant systems, fish were exposed to 5.0 mg/L Zn, 1.0 mg/L Cd, and 5.0 mg/L Zn + 1.0 mg/L Cd mixtures for 7 and 14 days and reduced glutathione (GSH) level, catalase (CAT), and glucose-6-phosphate dehydrogenase (G6PD) activities were investigated. In addition, Zn or Cd levels in whole blood were studied. Erythrocyte GSH level and CAT and G6PD enzyme activities increased in response to single and combined Zn and Cd exposure. The elevation observed in the CAT activity was higher in the Cd alone, and in combination with Zn, than in Zn alone. Time-dependent alteration was not observed in all antioxidant parameters. Exposure to metals (alone and in mixture) resulted in elevatation of Zn and Cd levels in the blood. Concentration of metals in the blood of fish exposed to the Zn + Cd combination was lower than in fish exposed to the single metal. This study demonstrates that metals caused oxidative stress in fish erythrocytes, and an adaptation with an increase in CAT and G6PD activities and GSH level, which were important in the protection against metal damage, was observed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jbt.20327 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Slow-Release Pharmaceutical Implants in Ecotoxicology: Validating Functionality across Exposure Scenarios.
ACS Environ Au
January 2025
Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.
Pharmaceutical contaminants have spread in natural environments across the globe, endangering biodiversity, ecosystem functioning, and public health. Research on the environmental impacts of pharmaceuticals is growing rapidly, although a majority of studies are still conducted under controlled laboratory conditions. As such, there is an urgent need to understand the impacts of pharmaceutical exposures on wildlife in complex, real-world scenarios.
View Article and Find Full Text PDFRare earth element erbium induces immune toxicity through the ROS/NF-κB pathway in zebrafish.
Fish Shellfish Immunol
January 2025
Jiangxi Province Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou, 341000, China. Electronic address:
The large-scale mining and utilization of rare earth elements have significantly increased their concentration in the environment, especially in regions surrounding mining areas. These environmentally-enriched rare earth elements accumulate in agricultural products and organisms through soil and water, potentially impacting in human health through the food chain. Erbium (Er), a rare earth element of the lanthanide series (Group IIIB), plays a crucial role in various modern technological applications.
View Article and Find Full Text PDFSex-specific reproductive toxicity of subacute exposure to glufosinate-ammonium in zebrafish (Danio rerio).
Sci Total Environ
January 2025
College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China; Hubei Engineering Technology Research Center for Aquatic Animal Disease Control and Prevention, Wuhan 430070, China. Electronic address:
Glufosinate-ammonium (GLA) is a common agricultural herbicide used worldwide. It can be transported into water bodies and can persist for long periods, posing a risk to non-target aquatic organisms. In this study, adult zebrafish were exposed to GLA (0, 0.
View Article and Find Full Text PDFRepeatability of critical thermal maximum (CT) in two freshwater ectotherms across contexts.
J Therm Biol
January 2025
Department of Biology, Trent University, Peterborough, ON, K9J 1Z8, Canada; Environmental and Life Sciences Graduate Program, Trent University, Peterborough, ON, K9J 5G7, Canada. Electronic address:
Critical thermal maximum (CT) is the most widely used method for quantifying acute upper thermal limits in ectotherms. CT protocol exposes animals to a consistent rate of environmental warming until they lose motor function. CT has been used to assess intraspecific variation among life stages, populations, or as a function of body size, often with the assumption that it is a durable and heritable trait at the individual level.
View Article and Find Full Text PDFAssessing Changes in Permethrin Toxicity to Juvenile Inland Silversides (Menidia beryllina) Under Different Temperature Scenarios.
Arch Environ Contam Toxicol
January 2025
Center for Fisheries, Aquaculture and Aquatic Sciences, School of Biological Sciences, Southern Illinois University, Carbondale, IL, 62901, USA.
Aquatic systems are impacted by temperature fluctuations which can alter the toxicity of pesticides. Increased temperatures related to climate change have elevated pest activity, resulting in an escalation of pesticide use. One such pesticide class, pyrethroids, has replaced the use of several banned pesticides due to its low mammalian toxicity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!