Purpose: This study described developmental changes in treadmill (TM) stepping and physical activity (PA) of infants at risk for neuromotor delay (ND) and explored these changes by diagnosis of cerebral palsy (CP). Relationships of stepping and PA with walking onset were examined.
Method: Fifteen infants at risk for ND (9.9 +/- 2.4 months) were tested every 2 months on a TM until walking onset or 24 months of corrected age. We recorded PA profiles using an activity monitor. Throughout the study, 6 of the 15 infants received a CP diagnosis.
Results: Infants increased alternating steps (AltStp), decreased toe contacts, and increased high-level PA. Infants with CP showed less AltStp, more toe contacts, and less high-level PA than those without CP. Infants' AltStp and high-level PA revealed a positive correlation to earlier onset of walking.
Conclusion: Future studies should examine whether a TM intervention could improve mobility in infants at risk for ND.
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http://dx.doi.org/10.1097/PEP.0b013e3181ccc8c6 | DOI Listing |
Allergol Int
December 2024
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Background: Identification of predictive biomarkers is crucial for formulating preventive interventions and halting the progression of atopic march. Although controversial, the use of accessible markers to predict or detect early onset of atopic diseases is highly desirable. Therefore, this study aimed to investigate whether corneal squamous cell carcinoma antigen-1 (SCCA1) collected from infants can predict the development of atopic dermatitis and food allergy.
View Article and Find Full Text PDFBMJ Open
December 2024
Laboratory of Human Milk and Lactation Research, Department of Medical Biology, University of Warsaw, Warsaw, Poland.
Introduction: Donor human milk (DHM) is the first alternative if mother's own milk is unavailable or contraindicated. Much DHM research has focused on its nutritional, immunological and biochemical composition in response to various maternal variables, standard human milk banking procedures and storage protocols. The current systematic review protocol, however, aims to systematically gather and analyse existing data pertaining to the impact of these aforementioned factors on the clinical, health-related and developmental outcomes observed in infants fed with DHM.
View Article and Find Full Text PDFBMJ Glob Health
December 2024
Division of Water and Health, Ethiopian Institute of Water Resources, Addis Ababa University, Addis Ababa, Ethiopia.
Background: In developing countries, due to improper management of domestic animals' exposures, under-five (U5) children have been affected by diarrhoea. However, there is no evidence that shows the presence of diarrhoea-causing pathogens in the faeces of U5 children and animals residing in the same houses in the Sidama region, Ethiopia.
Methods: A laboratory-based matched case-control study was conducted on children aged 6-48 months in the Sidama region of Ethiopia from February to June 2023.
Exp Neurol
December 2024
Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University, Cleveland, OH, United States of America. Electronic address:
Neonatal sepsis results in significant morbidity and mortality, but early detection is clinically challenging. In a neonatal rat model of endotoxic shock, we identified unique infrared thermographic (IRT) profiles in skin temperature that could identify risk of later mortality. Ten-day old rats were placed in a thermally stable isolette and IRT images of cranial (T), scapula (T) and rump (T) skin temperature were obtained continuously for 8 h following an intraperitoneal injection of LPS (or saline).
View Article and Find Full Text PDFChild Abuse Negl
December 2024
Department of Functional Brain Imaging, Institute of Development, Aging and Cancer (IDAC), Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan; Smart-Aging Research Center, IDAC, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Background: Early intervention may prevent maltreatment during infancy. This study examined the effectiveness of interventions initiated during the perinatal period to prevent child abuse and neglect.
Methods: We searched the MEDLINE, PsycINFO, Embase, and Cochrane Central Register of Controlled Trials databases for articles published before February 2023.
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