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Rare Coexistence: Giant Cell Tumor Recurrence and Infection in the Proximal Tibia - A Case Report.
J Orthop Case Rep
January 2025
Department of Orthopedics, Apollo sage hospitals, Bhopal, Madhya Pradesh, India.
Introduction: Giant cell tumor of bone (GCTB) ranks among the most prevalent locally aggressive tumor lesions, displaying a diverse range of biological behaviors. Recurrence of GCTB is well-documented, often attributed to microscopic tumour remnants remaining after intralesional curettage, with increased concern when infection occurs postoperatively. Studies suggest the limited effectiveness of adjuvants in preventing giant cell tumour recurrence, emphasizing the necessity of complete removal of malignant cells.
View Article and Find Full Text PDFGiant Cell Tumor of Distal Radius Treated with Wide Local Excision and Reconstruction with Ipsilateral Proximal Fibular Autograft - A Follow-Up.
J Orthop Case Rep
January 2025
Department of Orthopaedics, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Introduction: Giant cell tumour or osteoclastoma is benign, locally aggressive tumor with bone destruction and with malignant potential. It accounts for 5% of all primary bone tumor and occurs in skeletally mature individuals in the age group of 30 to 45 with peak incidence in the 3rd decade. GCT is more common in females.
View Article and Find Full Text PDFTeratocarcinosarcoma of the nasal cavity: challenges in the clinico-pathologic perspectives.
Eur Arch Otorhinolaryngol
December 2024
Department of Otorhinolaryngology and Head-Neck Surgery, All India Institute of Medical Sciences, Kalyani, NH-34 Connector, Basantapur, Saguna, Nadia, Kalyani, West Bengal, 741245, India.
Objective: Clinicopathologic illustration of sinonasal teratocarcinosarcoma (SNTCS) in a middle-aged man, highlighting the difficulties and challenges encountered during surgical intervention, histopathologic diagnosis, and its overall management.
Methodology: Case report and literature review.
Results: A 40-year-old man having recurrent epistaxis for three months presented with a dark-colored protruding polypoid nasal mass.
Glutathione peroxidase 4 overexpression induces anomalous subdiffusion and impairs glioblastoma cell growth.
J Biol Eng
December 2024
Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA.
Glioblastoma tumors are the most common and aggressive adult central nervous system malignancy. Nearly all patients experience disease progression, which significantly contributes to disease mortality. Recently, it has been suggested that recurrent tumors may be characterized by a ferroptosis-prone phenotype with a significant decrease in glutathione peroxidase 4 (GPx4) expression.
View Article and Find Full Text PDFVoltage-Induced Bromide Redox Enables Capacity Restoration of Fast-Charging Batteries.
Adv Mater
December 2024
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang Province, 310027, China.
Fast-charging lithium-ion batteries (LIBs) are essential for electric vehicles (EVs) to compete with conventional gasoline ones in terms of charging viability, yet the aggressive capacity drop in fast-charging scenarios gives rise to concerns regarding durability and sustainability. Herein, it is clarified that for fast-charging batteries, the excessive lithium (Li) plating on graphite anode inevitably brings capacity fading, and the concurrent accumulation of LiO-dominant passivation species that form dead Li is the main reason for their poor rechargeability. To refresh the passivated graphite, a voltage-induced activation mechanism is developed to leverage bromide (Br/Br ) redox couple for LiO and isolated Li activation in situ.
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