Background: Bupropion's efficacy for smoking cessation in pregnant women is unknown.
Objectives: To determine if substance-dependent women prescribed bupropion smoked fewer cigarettes/day than those prescribed citalopram/escitalopram or no antidepressant medication.
Methods: Comparison of smoking in bupropion (n = 11), citalopram/escitalopram (n = 17), and no antidepressant (n = 28) groups.
Results And Conclusions: Trend for greater decrease in smoking for the bupropion vs. citalopram/escitalopram group [-6.4 vs. -.4 cigarettes/day (p = .276)], although the bupropion decrease was similar to that seen in the no antidepressant group [-5.3 cigarettes/day].
Scientific Significance: Data support continued study of bupropion in depressed pregnant substance-dependent smokers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925391 | PMC |
| http://dx.doi.org/10.3109/00952990903544844 | DOI Listing |
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