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Article Abstract
Four new bromophycolides, R-U (1-4), were isolated from the Fijian red alga Callophycus serratus and were identified by 1D and 2D NMR and mass spectroscopic analyses. These compounds expand the known structural variety of diterpene-benzoate macrolides and exhibited modest cytotoxicity toward selected human cancer cell lines. Bromophycolide S (2) also showed submicromolar activity against the human malaria parasite Plasmodium falciparum.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375676 | PMC |
| http://dx.doi.org/10.1021/np900686w | DOI Listing |
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