Design and finite-element evaluation of a versatile assembled lumbar interbody fusion cage.

Introduction: When an interbody cage is inserted into a human being's lumbar spine, not only the design, but also the material used is considerably crucial, particularly when minimally invasive lumbar fusion (MILIF) approaches are considered. The purpose of this study was to design a multi-function cage (either for MILIF or open lumbar interbody fusion) and also to evaluate the strength of the design based on a finite-element model analysis.

Method: Three-dimensional finite-element models that were instrumental in the reproduction of post-operative conditions under which different cages, such as assembled lumbar interbody fusion cages (ALIFC) and the separated ones, could be examined and traced after implantation were developed. Simulations were run to realize various loading conditions including axial compression, flexion, extension, lateral bending and rotation under a constant compressive preload. Meanwhile, the evaluation results derived from FEMs data focused on endplate stress distribution, peak stress of von Mises and stress of cage. Stress distributions on the bone surface were evaluated and discussed as well.

Results: The consequences of cage insertion, high strains and stresses, were concentrated in the areas where the cage and endplate were in contact with each other. Simultaneously, contact stresses around the implants seemed to be concentrated around the periphery of the device. After implantation of ALIFC, the stiffness of the new cages was similar to that of traditional cages in an assemble condition, according to the biomechanical data dealing with FEM. Once a separated cage was in the place of an assembled cage, the stresses would get symmetrically distributed in the lateral areas of the endplate and decrease significantly at the center where the separated cage was not in contact with the endplate. The stress of the cage was going to be high once being rotating; most significant difference of stresses distribution due to the alternative choice has been found in the state of rotation. On comparison of peak von Mises stresses on the endplates in the new cage, the stresses were symmetrically distributed in the lateral areas of the endplate when a separated cage was used in place of an assembled cage.

Conclusion: The new cage was more advantages with regard to endplate stress distribution, peak stress of von Mises and stress of cage than the assembled state. ALIFC can provide sufficient primary stability for lumbar intervertebral fusion and the new cage may be regarded as a suitable device for load-bearing implantation.