Desmoplastic infantile gangliogliomas (DIGG) are low-grade (WHO Grade I) tumors of early childhood rarely occurring in older children and young adults. The mainstay of treatment is surgical. We report two older children with DIGG, both showing atypical radiology. One case was treated with radiation. The recurrence treated with only surgical excision showed excellent response to treatment.
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http://dx.doi.org/10.4103/0028-3886.59482 | DOI Listing |
JAMA Netw Open
January 2025
Coronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Importance: Multisystem inflammatory syndrome in children (MIS-C) is an uncommon but severe hyperinflammatory illness that occurs 2 to 6 weeks after SARS-CoV-2 infection. Presentation overlaps with other conditions, and risk factors for severity differ by patient. Characterizing patterns of MIS-C presentation can guide efforts to reduce misclassification, categorize phenotypes, and identify patients at risk for severe outcomes.
View Article and Find Full Text PDFPaediatr Drugs
January 2025
Department of Dermatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Background: The effectiveness of crisaborole for proactive treatment of atopic dermatitis (AD) is not well established.
Objectives: This study aims to investigate the efficacy and safety of a proactive treatment strategy with 2% crisaborole ointment for managing mild-to-moderate AD in children.
Patients And Methods: In this 16-week randomized-controlled trial, children aged 2-17 years with mild-to-moderate AD were enrolled.
Cleft Palate Craniofac J
January 2025
Seattle Children's Hospital, Craniofacial Center, Seattle, WA, USA.
Objective: To investigate whether differences in early cleft care increase risk of velopharyngeal insufficiency (VPI) after maxillary advancement.
Design: Retrospective cohort study.
Setting: Large pediatric tertiary care hospital.
Acta Ophthalmol
January 2025
Bartiméus Diagnostic Center for Complex Visual Disorders, Zeist, The Netherlands.
Purpose: The Teller Acuity Card (TAC) procedure is a preferential-looking method to assess visual acuity in infants and preverbal children and provides a quantitative measure of grating acuity. Several studies containing reference values have been published, the majority based on an older version of the TAC card set. In 2003, a new version of the TAC was released, called the TAC II.
View Article and Find Full Text PDFLaryngoscope
January 2025
Department of Otolaryngology, Jacobs School Medicine and Biomedical Sciences at the University at Buffalo, Buffalo, New York, USA.
Objective: Post-tonsillectomy hemorrhage (PTH) rates have increased in children over the last decade. This study aimed to determine whether PTH incidence in adults had also increased over the last 15 years.
Study Design: Retrospective study.
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