The bicyclic 5-amino-3-azabicyclo[3.3.0]octanes were shown to be effective replacements for the 3-amino-8-azabicyclo[3.2.1]octane found in the CCR5 antagonist maraviroc.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2010.01.080DOI Listing

Publication Analysis

Top Keywords

ccr5 antagonist
8
antagonist maraviroc
8
evaluation 3-amino-8-azabicyclo[321]octane
4
3-amino-8-azabicyclo[321]octane replacement
4
replacement ccr5
4
maraviroc bicyclic
4
bicyclic 5-amino-3-azabicyclo[330]octanes
4
5-amino-3-azabicyclo[330]octanes effective
4
effective replacements
4
replacements 3-amino-8-azabicyclo[321]octane
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!