AI Article Synopsis
- Familial hyperparathyroidism encompasses multiple endocrine neoplasia types 1 and 2A, as well as familial isolated primary hyperparathyroidism, which is a rare variety often caused by four-gland hyperplasia or a single-gland adenoma.
- A successful case is described involving a 24-year-old woman treated for familial isolated primary hyperparathyroidism through the resection of a double adenoma, facilitated by intraoperative parathyroid hormone (PTH) monitoring.
- Double adenoma should be included in the differential diagnosis for familial isolated primary hyperparathyroidism, and the use of intraoperative PTH levels combined with minimal-access surgery shows potential in treatment.
Article Abstract
Familial hyperparathyroidism includes the diagnoses of multiple endocrine neoplasia type 1, type 2A, and familial isolated primary hyperparathyroidism. Familial isolated primary hyperparathyroidism is a rare, distinct form of familial primary hyperparathyroidism, mainly due to four-gland hyperplasia or single-gland adenoma. We describe our success in treating a 24-year-old woman with familial isolated primary hyperparathyroidism with resection of double adenoma, using the guide of intraoperative parathyroid hormone (PTH) monitoring. Familial isolated primary hyperparathyroidism usually presents with four-gland hyperplasia or single-gland adenoma. However, double adenoma should be considered in the differential diagnosis. Using intraoperative parathyroid hormone levels and minimal-access surgery in familial isolated primary hyperparathyroidism may be promising.
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| http://dx.doi.org/10.1097/SMJ.0b013e3181d0fe11 | DOI Listing |
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