Peak expiratory flow (PEF) monitoring has long been a mainstay of asthma management, but controversy surrounds its efficacy in the pediatric population, and little published research exists on the subject. PEF is both effort and technique dependent and is not suitable for use in children under the age of 5 or with developmental disabilities. However, PEF is useful for monitoring airway changes if used properly, especially in that segment of the population labeled as "poor perceivers" of worsening symptoms. The authors review existing literature on the subject, including the newly revised National Heart, Lung, and Blood Institute (National Heart, Lung, and Blood Institute, National Institutes of Health, U.S. Department of Health and Human Services. (2007). Expert panel report 3: Guidelines for the diagnosis and management of asthma-full report 2007. Retrieved June 17, 2008, from http://www.nhlbi.nih.gov/guidelines/asthma/asthgdln.htm) evidence-based guidelines.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.pedn.2008.06.009 | DOI Listing |
Clin Exp Allergy
January 2025
School of Infection, Inflammation and Immunology, University of Birmingham, Brimingham, UK.
Data regarding Penicillin allergy labels (PALs) from India and Sri Lanka are sparse. Emerging data suggests that the proportion of patients declaring an unverified PAL in secondary care in India and Sri Lanka (1%-4%) is lesser than that reported in High Income Countries (15%-20%). However, even this relatively small percentage translates into a large absolute number, as this part of the world accounts for approximately 25% of the global population.
View Article and Find Full Text PDFStat Med
February 2025
Department of Biostatistics and Health Data Science, University of Pittsburgh, Pittsburgh, Pennsylvania.
An important aspect of precision medicine focuses on characterizing diverse responses to treatment due to unique patient characteristics, also known as heterogeneous treatment effects (HTE) or individualized treatment effects (ITE), and identifying beneficial subgroups with enhanced treatment effects. Estimating HTE with right-censored data in observational studies remains challenging. In this paper, we propose a pseudo-ITE-based framework for analyzing HTE in survival data, which includes a group of meta-learners for estimating HTE, a variable importance metric for identifying predictive variables to HTE, and a data-adaptive procedure to select subgroups with enhanced treatment effects.
View Article and Find Full Text PDFJ Asthma
January 2025
Medical Department, Fundación Neumológica Colombiana, Bogotá, Colombia.
Severe asthma burdens patients and presents clinical management challenges for healthcare professionals. Biologics are crucial interventions for severe type two (T2) patients with high eosinophil counts. We conducted a Delphi consensus in seven developing or typically underrepresented countries to understand expert agreement on managing severe asthma with type two (T2) inflammation.
View Article and Find Full Text PDFJ Asthma
January 2025
General Practitioner, Independent Scholar, Tehran, Iran.
Objective: Current literature acknowledges the complexity of exacerbation triggers in patients with asthma. We studied the clinical heterogeneity of patients with asthma exacerbation suspected of having pulmonary embolism using cluster analysis and compared the clusters regarding of the risks for pulmonary embolism.
Methods: In a secondary analysis of a dataset from the University of Florida, USA, individuals who experienced asthma exacerbation between June 2011 and October 2018 were included.
Explor Res Clin Soc Pharm
March 2025
College of Pharmacy, Qatar University, PO Box 2713, Doha, Qatar.
Background: Asthma self-management is an effective approach that empowers patients with asthma to control their condition and reduce its impact on their daily lives.
Objective: This systematic review aims to synthesize evidence regarding the knowledge, perceptions, facilitators, and barriers related to asthma self-management among patients.
Methods: A systematic literature search was conducted across five databases (PubMed, Science Direct, Scopus, Web of Science, and Google Scholar) using specific key terms.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!