Development of a Quality Checklist Using Delphi Methods for Prescriptive Clinical Prediction Rules: the QUADCPR.

Objective: Clinical prediction rules (CPRs) are clinician decision-making aids designed to improve the accuracy of a variety of decisions made during patient care. To our knowledge, there are no formally developed consensus-based guidelines designed to provide standards for the creation of CPRs.

Methods: The study used a 3-round Delphi method for consensus of a quality checklist initially developed based on recommendations derived from the literature. The 9 Delphi participants were randomly selected from the authors of peer-reviewed publications of prescriptive CPRs.

Results: During the 3 rounds, the Delphi participants modified the originally derived checklist and, based on a consensus standard, agreed upon a final 23-item checklist, which involved 4 constructs: (1) sample and participants, (2) outcome measures, (3) quality of tests and measures, and (4) statistical assumptions.

Conclusions: Use of the checklist has potential for improving the design and reporting of future prescriptive CPRs.