AI Article Synopsis
- Volatile sulphur compounds are the main cause of bad breath, and a new tool has been developed to detect and measure its intensity.
- The colorimetric sensor works by reacting iodine with hydrogen sulfide present in mouth air, allowing for a precise evaluation of oral malodour.
- The sensor has a low detection limit and shows strong correlation with existing methods, making it a promising clinical tool for assessing bad breath in patients.
Article Abstract
Volatile sulphur compounds are the primary constituents of oral malodour. Quantitative tools for the detection of oral malodour are beneficial to evaluate the intensity of malodour, analyse its causes and monitor the effectiveness of customized treatments. We have developed an objective, cost effective, do-it-yourself colorimetric sensor for oral malodour quantification. The sensor consisted of a sensing solution, a gas sampling unit for collecting a known volume of mouth air and a photometric detector. The sensing solution was iodine and the depletion of iodine on reaction with hydrogen sulphide was detected colorimetrically using starch. The detection limit of the sensor is 0.05 microg L(-1) of hydrogen sulphide, which is fit-for-purpose for oral malodour detection in healthy subjects as well as halitosis patients. Volatile sulphur compounds in mouth air were quantified in healthy human volunteers using this portable sensor and the detected levels were in the range of 0.2-0.4 microg L(-1). There was a good correlation between the VSC levels detected by the colorimetric sensor and halimeter (R(2)=0.934). The developed sensor can be easily fabricated in the laboratory, and it shows high potential to be used as a clinical evaluation tool for oral malodour assessments.
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| http://dx.doi.org/10.1016/j.aca.2009.11.064 | DOI Listing |
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