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Malformations vs. Neoplasia in the Oral Cavity: Special Emphasis on Mixed Odontogenic Tumors.
J Oral Pathol Med
January 2025
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Article Synopsis
- The terminology used to describe developmental lesions in the oral cavity can be confusing, particularly in distinguishing between developmental malformations and neoplasia, especially in odontogenic tumors.
- The report discusses the definitions of malformations and neoplasia, highlighting their significance within the context of odontogenic tumors.
- Understanding these concepts is crucial for accurately classifying and treating mixed odontogenic lesions.
Giant Complex Odontoma of the Posterior Mandible: A Case Report.
Cureus
September 2024
Department of Oral Pathology, Kothiwal Dental College and Research Centre, Moradabad, IND.
Complex odontoma is a benign odontogenic tumor composed of disorganized dental tissues, including enamel, dentin, cementum, and pulp. Unlike compound odontomas, which exhibit tooth-like structures, complex odontomas form a mass without anatomical organization. These tumors frequently present without symptoms and are typically identified inadvertently during standard dental imaging procedures.
View Article and Find Full Text PDFAre Ameloblastic Fibroma-related Lesions True Tumors?: Evidence Through CNA and BRAF Mutation Analysis.
Am J Surg Pathol
October 2024
Department of Oral Pathology, Peking University School and Hospital of Stomatology.
Ameloblastic fibroma (AF) and related lesions, namely ameloblastic fibrodentinoma (AFD) and ameloblastic fibro-odontoma (AFO), span a spectrum from true neoplasms to hamartomas. The 2017 World Health Organization classification proposes that AFD and AFO are precursors to odontomas, yet their precise nature remains uncertain. This study examined 19 AF cases, 4 AFD, 15 AFO, 19 odontomas (OD, 14 complex, 5 compound), and 2 ameloblastic fibrosarcomas (AFS), focusing on clinical characteristics, recurrence, and molecular profiles.
View Article and Find Full Text PDFMandibular Odontogenic Tumors That Caused Delayed Eruption of the First Molar: A Case Report of Two Patients.
Cureus
August 2024
Department of Oral and Maxillofacial Surgery Ⅱ, Nihon University School of Dentistry, Tokyo, JPN.
Article Synopsis
- Delayed eruption of permanent teeth is common, but impaction of the mandibular first molar is rare, often caused by issues like odontogenic cysts and tumors.
- The article details two cases where odontogenic tumors led to the delayed eruption of the mandibular first molar in children, with specific diagnoses of ameloblastic fibro-odontoma and odontoma.
- Treatment involved curettage of the tumors and fenestration of the impacted molars, which resulted in the successful eruption of the first molar in both cases.
Epidemiology of odontogenic tumours and selected cysts diagnosed at a single New Zealand oral pathology centre- A 15-year retrospective study.
Oral Maxillofac Surg
December 2024
Department of Oral Diagnostic and Surgical Sciences, University of Otago, Dunedin, New Zealand.
Article Synopsis
- The research analyzed the occurrence of odontogenic tumors (OT) and certain cysts at an oral pathology center in New Zealand over 15 years, revealing that 1.8% of biopsies were identified as these conditions.
- The most common types identified were odontoma, ameloblastoma, and cemento-ossifying fibroma, with male patients and those diagnosed in the mandibular region being more prevalent.
- The study highlighted the importance of long-term monitoring for patients with OKC and ameloblastoma due to their recurrence rates of 15.2% and 13.7%, respectively.
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