Photoactivation of nuclear isomer (115m)In with a halflife of 4.48 h occurs by (60)Co gamma-ray irradiation. This is because the resonance gamma-ray absorption occurs at 1078 keV level for stable (115)In, and that energy gamma-rays are produced by Compton scattering of (60)Co primary gamma-rays. In this work, photoactivation of (115m)In was applied to estimate the dose rate distribution around a (60)Co irradiation source utilizing a standard dose rate taken by alanine dosimeter. The (115m)In photoactivation was measured at 10 to 160 cm from the (60)Co source. The derived dose rate distribution shows a good agreement with both alanine dosimeter data and Monte Carlo simulation. It is found that angular distribution of the dose rate along a circumference at radius 2.8 cm from the central axis shows +/- 10% periodical variation reflecting the radioactive strength of the source rods, but less periodic distribution at radius 10 and 20 cm. The (115m)In photoactivation along the vertical direction in the central irradiation port strongly depends on the height and radius as indicated by Monte Carlo simulation. It is demonstrated that (115m)In photoactivation is a convenient method to estimate the dose rate distribution around a (60)Co source.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1269/jrr.09083 | DOI Listing |
Biosci Microbiota Food Health
September 2024
Core Technology Laboratories, Asahi Quality & Innovations, Ltd., 1-1-21 Midori, Moriya-shi, Ibaraki 302-0106, Japan.
α-Cyclodextrin (αCD), a cyclic hexasaccharide composed of six glucose units, is not digested in the small intestine but is completely fermented by gut microbes. Recently, we have reported that αCD supplementation for nonathlete men improved their 10 km biking times. However, the beneficial effects of αCD on exercise are not yet fully understood.
View Article and Find Full Text PDFFront Allergy
December 2024
Respiratory Evaluation Sciences Program, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Background: Infant antibiotic use is associated with increased risk of asthma. We examined the population impact of antibiotic exposure in the first year of life on the burden of pediatric asthma in British Columbia, Canada, using simulation modeling.
Methods: We performed a Bayesian meta-analysis of empirical studies to construct dose-response equations between antibiotic exposure in the first year of life and pediatric (<19 years of age) asthma.
PeerJ
January 2025
Department of Oncology, Cancer Center, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, Guangzhou, China.
Purpose: The purpose of this study was to determine the efficacy and safety of low-dose radiotherapy (LDR) for postoperative local chest wall recurrence of breast cancer.
Methods: The records of 52 patients with postoperative local chest wall recurrent breast cancer treated at our cancer center from January 2019 to December 2022. The t-test was used to compare the means of the LDR group and non LDR group.
Immunopharmacol Immunotoxicol
February 2025
Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Septic shock involves severe systemic inflammatory reaction toward various invading species, such as microorganisms and microbial toxins. Such a response is complicated and characterized as being a dynamic and time-dependent phenomenon. During this response, a significant amount of pro-inflammatory cytokines may be produced, causing a rapid death rate in septic victims and occasionally leading to apoptosis of immune cells within the first hours of septic reaction.
View Article and Find Full Text PDFJ Headache Pain
January 2025
Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Background: Rimegepant, a novel oral calcitonin gene-related peptide receptor antagonist, has been recently approved for the acute migraine treatment. While its efficacy was confirmed in randomized clinical trials, no data is available regarding real-life effectiveness and tolerability. GAINER, a prospective, multicentric study, aimed to evaluate rimegepant effectiveness and tolerability in the real-world setting.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!