Ultrastructural deformity of ovarian follicles induced by different cryopreservation protocols.

Fertil Steril

Research Institute for Agriculture and Life Science, Seoul National University, Seoul, South Korea. Electronic address:

Published: September 2010

Ultrastructural deformities were monitored after cryopreservation of F1 (B6CBAF1) mouse ovaries by either slow freezing or vitrification. Vacuole formation in the ooplasm, zona pellucida, and the cytoplasm of follicular cells, and mitochondrial deformity were detected. These types of cryodamage demonstrated protocol specificity.

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http://dx.doi.org/10.1016/j.fertnstert.2009.12.029DOI Listing

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