AI Article Synopsis
- The study analyzed liver function and clinical characteristics in 122 patients with acute hepatitis E overlapped by other infections, compared to 40 patients with just acute hepatitis E.
- Although liver enzymes (ALT, AST, TBIL, DBIL) showed no significant differences between the groups, albumin and globulin levels differed notably when hepatitis E was combined with hepatitis B.
- Patients with overlapping infections experienced more severe complications, highlighting the need for closer monitoring and prevention strategies to reduce mortality.
Article Abstract
Objective: To compare the liver function index and clinical characters in 122 patients with acute hepatitis E virus overlapping with other infection.
Methods: The liver function index and clinical characters of 122 patients with acute hepatitis E virus overlapping infection and 40 patients with acute hepatitis E were retrospectively analyzed.
Results: No significant differences of ALT, AST, TBIL, DBIL were found between acute hepatitis E groups and overlapping infection hepatitis A or hepatitis B (P > 0.05). However, there were significant differences of Albumin (ALB) and Globulin (GLO) were found between acute hepatitis E groups and overlapping infection hepatitis B (P < 0.01). In acute hepatitis E overlapping infected hepatitis B or hepatitis A patients, more and severe complications were also observed.
Conclusion: The patients with acute Hepatitis E virus, especially Hepatitis E virus overlapping infection, need to pay more clinical monitor, prevent complication early and lower death rates.
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