[Human papillomavirus detection in clear cell carcinoma of the cervix].

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi

Department of Obstetrics and Gynaecology, PLA General Hospital, Beijing 100853, China.

Published: April 2009

Objective: To investigate the infection of the high risk human papillomavirus (HPV) in the specimen of the clear cell carcinoma of the cervix.

Methods: We extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimens from a 37-year-old patient with clear cell carcinoma of the cervix and detected the HPV genotype with the nested PCR.

Results: We identified HPV18, a high-risk genotype, in the specimens.

Conclusion: The HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffin-embedded specimens of clear cell carcinoma of the cervix (CCCC) with a high accuracy and sensitivity.

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