Audiological characteristics were investigated in 81 ears of 53 infants with abnormal transient evoked otoacoustic emission (TEOAE) and normal auditory brainstem response (ABR). The relationship between ABR and other hearing testing methods, including 40Hz auditory event-related potential (40Hz-AERP), auditory steady state response (ASSR), distortion product otoacoustic emission (DPOAE), tympanometry, and acoustic reflex, was analyzed. Of the 81 ears, 18 ears (22.2%) were normal, while 63 ears (77.8%) were abnormal according to the tests. Testing of the 40 Hz AERP (36 ears) and ASSR (45 ears) revealed that 14 ears (38.9%) and 27 ears (60.0%) were abnormal, respectively. Testing of DPOAE in 68 ears revealed that 50 ears (73.5%) were abnormal. Testing of tympanometry in 50 ears and acoustic reflex in 47 ears revealed that 9 ears (18%) and 27 ears (57.4%) were abnormal, respectively. The present data suggests that the hearing of infants cannot be sufficiently evaluated with ABR only and that it must be evaluated with integrative audiological testing methods.
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Ophthalmol Sci
October 2024
Department of Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey.
Objective: To investigate retinal vascular permeability mapping as a potential biomarker for diabetic retinopathy in subjects with diabetes with no signs of retinopathy and with mild nonproliferative retinopathy.
Design: This is a case-control study.
Subjects: Participants included 7 healthy controls, 22 subjects with diabetes mellitus and no clinical signs of retinopathy (DMnoDR), and 7 subjects with mild nonproliferative diabetic retinopathy (NPDR).
Cureus
November 2024
Trauma and Orthopaedics, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Popliteal artery entrapment syndrome (PAES) is a rare cause of exertional leg pain in young adults, which is caused by compression of the popliteal artery by the surrounding muscular structure. Due to significant overlap in symptoms with other conditions, limitations of diagnostic imaging, and lack of awareness, PAES is frequently misdiagnosed, resulting in late complications and poor prognosis. Clinical assessment is crucial in making the initial diagnosis and referring for relevant investigations for PAES.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Department of Otolaryngology Head and Neck Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
The current understanding of the human auditory system has been primarily based on studies using animal and cellular models. Organoids have been used to simulate cochlear structures and replicate cochlear functions. However, the physical and chemical cues required to control the development of cochlear organoids accurately remain poorly understood, limiting research advances on cochlea-on-a-chip systems.
View Article and Find Full Text PDFAnn Otol Rhinol Laryngol
December 2024
Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, USA.
Introduction: External ear malformations represent a spectrum of congenital anomalies that may involve the external auditory canal (EAC), tympanic membrane (TM), or associated structures. A rare anomaly, the EAC skin wedge, results from incomplete canalization during embryologic development. This report presents the clinical presentation, diagnostic evaluation, and surgical management of this condition.
View Article and Find Full Text PDFMicrob Pathog
December 2024
IDIAP, Ciudad del Saber, Panama.
Zea mays is the second most popular cereal crop in Panama. Its production is intended for human and livestock consumption but is threatened by several diseases. We report the occurrence of Fusarium ear rot, a disease that has affected corn production in a specific region of Panama.
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