Benzotetramisole-catalyzed dynamic kinetic resolution of azlactones.

Org Lett

Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA.

Published: February 2010

Enantioselective acyl transfer catalyst benzotetramisole (BTM) has been found to promote dynamic kinetic resolution of azlactones providing di(1-naphthyl)methyl esters of alpha-amino acids with up to 96% ee.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947837PMC
http://dx.doi.org/10.1021/ol902969jDOI Listing

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