Objective: To assess the sensitivity to change of two depression scales for stroke patients: the Aphasic Depression Rating Scale (ADRS), which is a 9-item external assessment, and the Visual Analog Mood Scale (VAMS), which is a visual self-assessment scale.
Patients: Forty-nine stroke patients admitted to two rehabilitation units.
Methods: Symptoms of depression were assessed twice at a one-month interval (D0-D30) using the ADRS, the VAMS, and by a trained psychologist (PSY). Sensitivity to change was assessed by effect size and standardized response mean. A one-way ANOVA on ranks was performed to determine if the scales distinguished between deteriorated, stable and improved patient status. Spearman's correlation coefficient (r) was used to assess the relationship between changes in PSY and changes in the ADRS and the VAMS between D0 and D30.
Results: Mean depression scores at D0 and D30 were 2.6 +/- 1.8 and 2.4 +/- 1.7 (ADRS/10), 3.1 +/- 2.9 and 3.0 +/- 3.2 (VAMS/10), 2.9 +/- 2.3 and 2.4 +/- 2.4 (PSY/10). Percentages of deteriorated, stable and improved patient status were 22%, 45% and 33% (ADRS); 41%, 22% and 37% (VAMS); and 20%, 41% and 39% (PSY). Changes in PSY correlated with the ADRS (r = 0.72, P<10( -6)) and the VAMS (r = 0.41, P<10(- 2)). The ADRS was better than the VAMS in terms of effect size, standardized response mean and ability to discriminate between deteriorated, stable and improved patient status. This result was partly due to the difficulty encountered by nine (19%) patients in understanding directions to complete the VAMS.
Conclusions: The ADRS is more sensitive than the VAMS for detecting changes in post-stroke depression. The VAMS is less appropriate in very cognitively impaired stroke patients.
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http://dx.doi.org/10.1177/0269215509346087 | DOI Listing |
This longitudinal study aimed to examine the long-term effects of Reminiscing and Emotion Training (RET), child maltreatment, and the COVID-19 pandemic on maternal elaboration and sensitive guidance during reminiscing. RET was developed to improve maternal elaborative and emotionally sensitive reminiscing among maltreating mothers of preschool-aged children. Of the original 248 mothers and their preschool-aged children who participated in the trial of RET, which included 165 families with maltreatment who were randomized to receive RET ( = 83) or a case management community standard condition (CS, = 82), and a group of demographically similar families with no history of child maltreatment, nonmaltreatment comparison (NC, = 83), 166 families participated in an assessment 5 years postintervention (Time 5; T5) at which children were aged 8-12 years.
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Hubei Key Laboratory of Genetic Regulation & Integrative Biology, Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, School of Life Sciences, Central China Normal University, Wuhan 430079, China.
Heme oxygenase-1 (HO-1) catalyzes heme degradation on the consumption of NADPH and molecular oxygen. As an inducible enzyme, HO-1 is highly induced in various disease states, including cancer. Currently, two fluorescent probes for HO-1 have been designed based on the catalytic activity of HO-1, in which the probes serve as a substrate, so NADPH is required to enable the detection.
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College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, Beijing, China.
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Çukurova University Faculty of Medicine, Department of Medical Microbiology, Adana, Türkiye.
Group B Streptococcus (GBS) or Streptococcus agalactiae is a pathogen that causes infections during pregnancy. The aim of this study was to investigate the antibiotic sensitivity profiles, capsule genotypes and biofilm forming capabilities of GBS isolates obtained from pregnant women . The study included 252 pregnant women who applied to Adana Gynecology and Children's Hospital between 2018 and 2023.
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