Background: Manual Therapy applied to patients with non specific neck pain has been investigated several times. In the Netherlands, manual therapy as applied according to the Utrecht School of Manual Therapy (MTU) has not been the subject of a randomized controlled trial. MTU differs in diagnoses and treatment from other forms of manual therapy.
Methods/design: This is a single blind randomized controlled trial in patients with sub-acute and chronic non specific neck pain. Patients with neck complaints existing for two weeks (minimum) till one year (maximum) will participate in the trial. 180 participants will be recruited in thirteen primary health care centres in the Netherlands.The experimental group will be treated with MTU during a six week period. The control group will be treated with physical therapy (standard care, mainly active exercise therapy), also for a period of six weeks.Primary outcomes are Global Perceived Effect (GPE) and functional status (Neck Disability Index (NDI-DV)). Secondary outcomes are neck pain (Numeric Rating Scale (NRS)), Eurocol, costs and quality of life (SF36).
Discussion: This paper presents details on the rationale of MTU, design, methods and operational aspects of the trial.
Trial Registration: ClinicalTrials.gov Identifier: NCT00713843.
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http://dx.doi.org/10.1186/1471-2474-11-14 | DOI Listing |
Lung Cancer
January 2025
Dept. of Medical Oncology, Princess Margaret Cancer Center, Toronto, ON, Canada.
Background: Manual extraction of real-world clinical data for research can be time-consuming and prone to error. We assessed the feasibility of using natural language processing (NLP), an AI technique, to automate data extraction for patients with advanced lung cancer (aLC). We assessed the external validity of our NLP-extracted data by comparing our findings to those reported in the literature.
View Article and Find Full Text PDFJ Consult Clin Psychol
January 2025
Department of Clinical Psychology, Faculty of Social and Behavioural Sciences, Utrecht University.
Objective: Sudden gains describe large and stable reductions in symptoms between two consecutive treatment sessions and have not yet been investigated in prolonged grief disorder (PGD), a new disorder in the 11th edition of the and text revision of the fifth edition of the characterized by separation distress and accompanying symptoms beyond 6 months of bereavement. The study aimed to examine the occurrence of sudden gains and their relation to treatment outcome and content during cognitive behavioral therapy (CBT) and supportive counseling for children and adolescents with PGD symptoms.
Method: We used data from 118 patients (50% female; age: = 12.
J Man Manip Ther
January 2025
Center for Rehabilitation Research, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Rev Esp Enferm Dig
January 2025
Aparato Digestivo , Hospital Universitario Infanta Sofía.
A 54-year-old male underwent a low anterior resection in 2015 for rectal adenocarcinoma. He presented to the emergency department with a two-week history of fever, perianal pain, an erythematous, warm, and actively draining mass. Physical examination revealed a perianal abscess in the left posterior gluteal region, with a palpable internal fistulous orifice 3 cm from the anal margin.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Center for Cognitive Disorders, Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar, Munich, Bavaria, Germany.
Background: The increasing number of people living with dementia and its burden on families and systems particularly in low- andmiddle-income countries require comprehensive and ecient post-diagnostic management. This study aimed to explore the acceptability and ecacy of a multi-professional case management and psychoeducation model (North Macedonia Interprofessional Dementia Care, or NOMAD) delivered bymobile teams for people with dementia and their caregivers in North Macedonia.
Method: We conducted a two-arm randomized controlled trial comparing the intervention with treatment as usual.
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