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Point/Counterpoint: The role of reirradiation in recurrent glioblastoma.
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Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
Point/Counterpoint #2: Current Clinical Considerations With Nonoperative Management of Rectal Cancer.
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Locally advanced rectal cancer has historically been treated with multimodal therapy consisting of radiation therapy, chemotherapy, and total mesorectal excision. However, recent prospective trials and registry studies have demonstrated similar disease outcomes with nonoperative management for patients who experience an excellent clinical response to radiation and chemotherapy. This article reviews data regarding nonoperative management for rectal cancer, and highlights current challenges and limitations in a point-counterpoint format, in the context of two clinical cases.
View Article and Find Full Text PDFWhich Modality of SFRT Should be Considered First for Bulky Tumor Radiation Therapy, GRID or LATTICE?
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Department of Radiation Oncology, University of Southern California, Los Angeles, CA.
Spatially fractionated radiation therapy (SFRT), also known as the GRID and LATTICE radiotherapy (GRT, LRT), the concept of treating tumors by delivering a spatially modulated dose with highly non-uniform dose distributions, is a treatment modality of growing interest in radiation oncology, physics, and radiation biology. Clinical experience in SFRT has suggested that GRID and LATTICE therapy can achieve a high response and low toxicity in the treatment of refractory and bulky tumors. Limited initially to GRID therapy using block collimators, advanced, and versatile multi-leaf collimators, volumetric modulated arc technologies and particle therapy have since increased the capabilities and individualization of SFRT and expanded the clinical investigation of SFRT to various dosing regimens, multiple malignancies, tumor types and sites.
View Article and Find Full Text PDFTreatment strategies for malignant pulmonary nodule: beyond lobectomy. Point-counterpoint.
Curr Opin Pulm Med
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Division of Vascular and Interventional Radiology, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine.
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View Article and Find Full Text PDFPoint-Counterpoint: What's in a Name? Cancer by Any Other Name Is Still Cancer: The Flawed Argument for Renaming Grade Group 1/Gleason Score 3+3=6 Disease.
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