Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BMC Biology on the culture of mammary gland epithelial cells, multiple parameters that influence the model must be taken into account.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871524 | PMC |
| http://dx.doi.org/10.1186/jbiol213 | DOI Listing |
Publication Analysis
Top Keywords
three-dimensional culture
8
apical polarity
4
polarity three-dimensional
4
culture systems
4
systems now?
4
now? delineation
4
delineation mechanisms
4
mechanisms establish
4
establish maintain
4
maintain polarity
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!