Background: Arterial wall imaging has been increasingly employed in clinical trials to evaluate the impact of medical therapies on progression of atherosclerosis.

Scope: A selective overview of major findings from clinical trials that assessed the impact of medical therapies on atherosclerosis progression.

Findings: Targeting established risk factors including LDL cholesterol, HDL cholesterol and blood pressure has a beneficial impact on disease progression.

Conclusion: As a result, vascular imaging has been employed in the early evaluation of experimental therapies.

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http://dx.doi.org/10.1185/03007990903547616DOI Listing

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