The bioptats of gingiva of 88 patients with different degree of periodontities on the background of hypothyreosis was studied. The histochemical and histoenzimochemical investigations were carried out. It was shown the decrease of fermental activity: mitochondrial breathing - oxydoreduqtases, glycolysis and in the same way terminal oxidation in the structures of ephythelial tissue and mucous membrane, especially in patients with middle severity periodontities.

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