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Identification and characterization of a methyl-accepting chemotaxis protein in Ralstonia pseudosolanacearum using chemically undefined materials.
J Gen Appl Microbiol
March 2025
Program of Biotechnology, Graduate School of Integrated Sciences for Life, Hiroshima University.
Ralstonia pseudosolanacearum is a plant-pathogenic bacterium that causes bacterial wilt in economically important crops. Chemotaxis is required for full virulence in R. pseudosolanacearum.
View Article and Find Full Text PDFThe emerging significance of furan fatty acids in food, nutrition, and potential therapeutic use.
Food Chem
March 2025
Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:
The emerging significance of furan fatty acids (FuFAs) is explored at the intersection of food, chemistry, nutrition, and therapeutics. FuFAs, with a distinctive furan ring incorporated into fatty acyl chains, are minor yet bioactive constituents of dietary lipids known for their unique chemical properties. This review examines FuFA biosynthesis in various organisms, highlighting their occurrence in food products.
View Article and Find Full Text PDFNetwork pharmacology and experimental analysis reveal Ethyl caffeate delays osimertinib resistance in lung cancer by suppression of MET.
Cancer Cell Int
March 2025
Department of Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Background: Fei Yanning Formula (FYN) is extensively applied in clinical lung cancer treatment. However, the specific active constituents and targets of its therapeutic effects remain unclear.
Objective: The study aims to explore the active constituents and mechanism of FYN in delaying osimertinib resistance by network pharmacology analysis and experimental verification.
The main active components of Prunella vulgaris L. alleviate myocardial ischemia-reperfusion injury by inhibiting oxidative stress and ferroptosis via the NRF2/GPX4 pathway.
J Ethnopharmacol
March 2025
Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Key Lab of Pharmacological Traditional Chinese Medicine Formulae, Ministry of Education, Tianjin 301617, China; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China; Endocrinology Department, Fourth Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China. Electronic address:
Ethnopharmacological Relevance: Prunella vulgaris L. (PV) is a widely distributed medicinal and edible plant used in traditional Chinese medicine for its anti-tumor, anti-inflammatory, anti-oxidant, hypoglycemic, and anti-hypertensive effects. Despite the numerous studies reporting on its cardiovascular protective effects, it is still not known whether PV could relieve myocardial ischemia-reperfusion (MI/R) injury.
View Article and Find Full Text PDFChemical composition, anti-microbial, and anti-cancer activity of essential oil from Tanacetum parthenium (L.) Sch.Bip leaves cultivated in Dalat, Vietnam.
Chem Biodivers
March 2025
Vietnam National Insitute of Medicinal Materials, Tay Nguyen research center of Medicinal Materials, Dalat, Dalat, VIET NAM.
The essential oil extracted from Tanacetum parthenium (L.) Sch.Bip.
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