AI Article Synopsis
- The study evaluated the anti-nociceptive and anti-inflammatory properties of ethanolic extracts from Glycine max (SoRiTae) and Rhynchosia nulubilis (Yak-Kong) seeds using various mouse models.
- Tests showed that both extracts significantly reduced swelling and pain compared to standard medications like aminopyrine and indomethacin.
- The findings suggest that SoRiTae and Yak-Kong seeds may be promising natural alternatives for pain and inflammation treatment.
Article Abstract
The aim of this study was to assess the in vivo potential of ethanolic extracts of Glycine max (L.) Merr. (SoRiTae) and Rhynchosia nulubilis (Yak-Kong) seeds as natural anti-nociceptive and anti-inflammatory agents. To assess the anti-nociceptive and anti-inflammatory potential, the ethanolic extracts of SoRiTae and Yak-Kong seeds were tested in arachidonic acid-induced ear edema, carrageenan induced paw edema, formalin-induced licking time, acetic acid induced writhing and hot plate-induced thermal stimulation in mice. The administration of ethanolic extracts of SoRiTae and Yak-Kong seeds evoked a significant effect of anti-nociceptive and anti-inflammatory activities as compared to standards aminopyrine and indomethacin. The ear edema, paw edema, paw licking time, pain and writhes in mice were significantly reduced (p < 0.05) as compared to the control. The results obtained in this study indicate that both SoRiTae and Yak-Kong soybeans possesses potential anti-nociceptive and anti-inflammatory activities.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808008 | PMC |
| http://dx.doi.org/10.3390/ijms10114742 | DOI Listing |
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