Study Design: Retrospective case series.
Objective: To present the technique and results of anterior cervical discectomy and fusion (ACDF) by using mesh cage reconstruction with autologous cancellous bone graft.
Background: Since the initial ACDF description by Bailey and Badgley, a variety of grafting techniques have been proposed. The primary disadvantage of autologous bone grafting is donor site pain when compared with allograft. However, autologous bone graft still remains the standard and cancellous bone retrieval through a cortical window minimizes subperiosteal stripping. This may improve donor site morbidity while providing the advantages of autologous bone graft.
Methods: Thirty-seven patients who had undergone ACDF with cancellous bone graft by using mesh cages and anterior plating with at least 6 months follow-up were reviewed. All patients had autologous cancellous bone graft harvested through a cortical window with limited subperiosteal striping. Bone graft was then packed into and around a titanium mesh cage that furnishes structural support.
Results: The principal diagnosis was radiculopathy in 30 patients, myeloradiculopathy in 2 patients, instability in 3 patients, and kyphosis in 2 patients. Sixty-four levels were fused: one 4-level fusion, eight 3-level fusions, eight 2-level fusions, and twenty 1-level fusions. All patients demonstrated improved neurologic function and resolution of preoperative pain postoperatively. The donor site for cancellous bone was the iliac crest in 33 patients and the manubrium in 4 patients. Perioperative donor site pain was absent in 35 of 38 patients by 6 weeks with resolution of donor site pain by 3 months in all patients. At most recent follow-up, no patients had donor site pain, no instrumentation failure, and no wound complications. Sixty-three of 64 (98.4%) of cervical segments fused. One pseudoarthrosis occurred in an attempted 4-level fusion, which fused after a second operation.
Conclusions: Autologous bone grafting with mesh cage reconstruction is an acceptable alternative to autologous tricortical structural graft or allograft with reduced donor site pain and excellent biologic arthrodesis.
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http://dx.doi.org/10.1097/BSD.0b013e3181aed73c | DOI Listing |
Foot Ankle Int
January 2025
Department of Orthopaedic Surgery, Chungbuk National University Hospital, Cheongju, Republic of Korea.
Background: Autologous osteochondral transplantation (AOT) is an option to treat large osteochondral lesions of the talus (OLTs), accompanying subchondral cyst, and previous unsuccessful bone marrow stimulation (BMS) procedures. Although there is extensive literature on the outcomes of surgical interventions for medial osteochondral lesions, research focusing on lateral lesions remains limited. This article presents the intermediate-term clinical and radiologic outcomes following AOT for lateral OLTs.
View Article and Find Full Text PDFFacial Plast Surg
January 2025
Department of Rhinology and Facial Plastic Surgery, Royal National ENT and Eastman Dental Hospitals, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Optimal results in complex nasal reconstruction, particularly in the context of post-traumatic and revision septorhinoplasty, often require the use of cartilage grafts to provide additional structural support to the nose. While autologous costal cartilage (ACC) has been traditionally used, this can be limited by donor site morbidity, increased operative time, and in some cases, lack of suitable cartilage for grafting. There has been a trend towards using irradiated homologous costal cartilage (IHCC) as an alternative source of graft material.
View Article and Find Full Text PDFActa Biomater
January 2025
Central laboratory of Liaocheng People's Hospital, Liaocheng, Shandong, 252000, China. Electronic address:
Peripheral nerve injury (PNI) as a common clinical issue that presents significant challenges for repair. Factors such as donor site morbidity from autologous transplantation, slow recovery of long-distance nerve damage, and deficiencies in local cytokines and extracellular matrix contribute to the complexity of effective PNI treatment. It is extremely urgent to develop functional nerve guidance conduits (NGCs) as substitutes for nerve autografts.
View Article and Find Full Text PDFJSES Int
November 2024
Department of Orthopaedic Surgery, University of Iowa, Iowa City, IA, USA.
Background: Limitations to using the knee as donor cartilage include cartilage thickness mismatch and donor site morbidity. Using the radial head as donor autograft for capitellar lesions may allow for local graft harvest without distant donor site morbidity. The purpose of this study is to demonstrate the feasibility of performing local osteochondral autograft transfer from the nonarticular cartilaginous rim of the radial head to the capitellum.
View Article and Find Full Text PDFSurg Technol Int
January 2025
Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
Thermal or burn injuries cause coagulative necrosis of the epidermis and underlying tissues and the resultant wounds can be long lasting and highly painful. Depending on the depth of a burn, management ranges from local wound care to surgical intervention. When presented with deep-partial thickness and full-thickness burns, autologous skin grafting has been the mainstay of management to prevent scarring and promote healing.
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