[Liver metastasis from sigmoid colon cancer showed a complete response to S-1 after recurrence with FOLFOX6 treatment].

A 48-year-old woman was referred to our hospital with complaints of appetite loss caused by a sigmoid colon cancer and multiple liver metastasis. To prevent bowel obstruction, a sigmoid colon resection was performed. On postoperative day 27, FOLFOX was begun for the liver metastasis. But FOLFOX6 was discontinued due to diarrheal symptoms of grade 3. The liver metastasis was pointed out again in CT after two months, and S-1 was begun. It became CR on CT again. S-1 can be expected to be an effective agent for the treatment of colon cancer with liver metastasis.