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Non-smoking, non-drinking, oral squamous cell carcinoma patients are a distinct and clinically significant group.
Oral Maxillofac Surg
January 2025
Department of Maxillofacial Surgery, Elizabeth University Hospital, 1345 Govan Rd, Glasgow, Queen, UK.
Purpose: Carcinogenesis of oral squamous cell carcinoma (OSCC) has long been associated with exposure to tobacco smoke and alcohol consumption. Some centres have reported that non-smoking non-drinking (NSND) patients represent a significant and increasing proportion of OSCC cases with reports of poorer outcomes. Demographic characteristics are variably reported for this group and carcinogenesis is not fully understood.
View Article and Find Full Text PDFPhysicians' required competencies in AI-assisted clinical settings: a systematic review.
Br Med Bull
January 2025
Department of Bioethics & Health Humanities, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Background: Utilizing Artificial Intelligence (AI) in clinical settings may offer significant benefits. A roadblock to the responsible implementation of medical AI is the remaining uncertainty regarding requirements for AI users at the bedside. An overview of the academic literature on human requirements for the adequate use of AI in clinical settings is therefore of significant value.
View Article and Find Full Text PDFPrevalence and determinants of restrictive lung disorder among quarry workers at the Umuoghara quarry site, Ebonyi State, Nigeria: a cross-sectional study.
BMC Pulm Med
January 2025
Institute of Public Health, University of Nigeria, Enugu, Nigeria.
Introduction: Respiratory disorders pose a serious health risk for quarry workers exposed to dust, as they are a leading source of morbidity and mortality globally, often resulting in irreversible lung conditions. This study assessed the prevalence and determinants of restrictive disorder among quarry workers in Umuoghara quarry site, Ebonyi State.
Methods: This study was done on quarry workers at the Umuoghara quarry site, Ebonyi State.
Effects of Tongluo Zhitong formula on synovial fibroblast proliferation in human knee osteoarthritis.
Heliyon
January 2025
Department of Orthopedics, Beijing LongFu Hospital, Beijing, China.
Objective: We aimed to investigate the effects of Tongluo Zhitong formula on synovial fibroblast proliferation in human knee osteoarthritis (KOA).
Methods: Discarded synovial tissue collected from patients undergoing total knee arthroplasty at our hospital was digested with type I collagenase. Primary culture was performed on three to four generations of fibroblasts, which were treated with high, medium, and low concentrations of Tongluo Zhitong formula.
Ankyloglossia and breastfeeding self-efficacy in newborns: a birth cohort study.
BMC Oral Health
January 2025
Department of Pediatric Dentistry, School of Dentistry, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Background: The impact of ankyloglossia (tongue-tie) on breastfeeding outcomes may be overestimated and surgical treatment in newborns remains a controversial topic. The aim of the present study was to assess and quantify the impact of ankyloglossia in newborns on breastfeeding self-efficacy at 14 days of life.
Methods: A birth cohort study was conducted involving mothers and newborns soon after childbirth at a public hospital in the city of Canoas, southern Brazil.
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