Female animals tolerate trauma and hemorrhage better than male animals AND Estrogen has rapid nongenomic effects that protect organs from damage and attenuate insult-induced inflammation MOREOVER The survival deficit from trauma and hemorrhage produced in ovariectomized female animals is repaired with administration of exogenous estrogen AND Women survive injury, sepsis, and trauma-hemorrhage-induced hypoxemia/reperfusion better than men THEREFORE Women rule ... in survival after trauma, thus, men would benefit from being more like women.
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http://dx.doi.org/10.1016/j.surg.2009.04.033 | DOI Listing |
Eur J Case Rep Intern Med
December 2024
Department of Geriatrics and Internal Medicine, Champmaillot Hospital, University Hospital, Dijon, France.
Introduction: According to the World Health Organization, 44 million people worldwide suffer from Alzheimer's disease. Abnormal movements are atypical symptoms of Alzheimer's disease.
Case Description: An 87-year-old woman, followed for Alzheimer's disease, experienced abnormal movements.
Anal Bioanal Chem
January 2025
Chemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD, 20899, USA.
Commutability is where the measurement response for a reference material (RM) is the same as for an individual patient sample with the same concentration of analyte measured using two or more measurement systems. Assessment of commutability is essential when the RM is used in a calibration hierarchy or to ensure that clinical measurements are comparable across different measurement procedures and at different times. The commutability of three new Standard Reference Materials (SRMs) for determining serum total 25-hydroxyvitamin D [25(OH)D], defined as the sum of 25-hydroxyvitamin D [25(OH)D] and 25-hydroxyvitamin D [25(OH)D], was assessed through an interlaboratory study.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Background: Dementia diagnosis presents global healthcare challenges due to its elusive nature and inconsistent documentation in Electronic Health Records (EHRs). Approaches relying on diagnostic codes and rules may overlook undiagnosed cases or mistakenly identify others, as these codes are frequently used for purposes beyond disease diagnosis. This highlights the need for more sophisticated diagnostic tools.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Amgen Biotechnology Research, Thousand Oaks, CA, USA.
Background: Late-life exposure to PM is a risk factor for Alzheimer's disease (AD) and related dementias. Accelerated brain aging associated with PM exposure likely takes place at preclinical stage. In Feb.
View Article and Find Full Text PDFPharmacoepidemiol Drug Saf
January 2025
Department of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts, USA.
Purpose: To comply with the Health Insurance Portability and Accountability Act of 1996 (HIPAA) Privacy Rule, many real-world data providers mask a patient's date of birth by supplying only year of birth to data users. The lack of granularity around patient age is a challenge when using RWD, especially for pediatric research studies. In this study, a proxy for patient date of birth is evaluated using electronic health record (EHR) data.
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