Objective: To observe the efficacy of nasal glucocorticoid continuously used for 12 weeks on nasal obstruction in patients with persistent non-allergic rhinitis (PNAR).
Methods: The changes of nasal obstruction, nasal resistance, nasal mucous membrane and quality of life in 47 patients with PNAR were observed. The efficacy of nasal glucocorticoid (Mometasone Furoate Nasal Spray, MFNS 200 microg/day) on patients with PNAR was evaluated.
Results: The results of nasal glucocorticoid (MFNS) continuously used for 12 weeks demonstrated: (1) After treatment, the nasal obstruction, nasal discharge, nasal obstruction related dizziness, headache, hyposmia, daily life activity, whole body fatigue, mental status were significantly improved (P < 0.05). (2) Nasal resistance showed significant amelioration (pre-treatment = 0.28 +/- 0.10, post- treatment = 0.16 +/- 0.05; F = 91.471, P < 0.05). (3) SF-36 questionnaire revealed that role physical, bodily pain, general health, role emotional had significant amelioration (P < 0.01). (4) SNOT-20 questionnaire revealed that the defatigation, impaired concentration, pinch the nose, nasal discharging into the throat, sleep quality had significant amelioration (P < 0.01). (5) Continued treatment for 12 weeks was better than 4 weeks, continued treatment had good effect.
Conclusion: The study shows that nasal glucocorticoid improved the nasal obstruction, nasal resistance, nasal mucous membrane and quality of life in patients with PNAR.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Clinical Manifestations, Prognostic Factors, and Outcomes of Extranodal Natural Killer T-Cell Lymphoma: A Single-Center Experience in Thailand.
Hematol Rep
November 2024
Department of Internal Medicine, Faculty of Medicine, Chiang-Mai University, Chiang-Mai 50200, Thailand.
: The primary objective of this study was to investigate clinical manifestations, time to diagnosis, and number of biopsies in patients with extranodal natural killer T-cell lymphoma (ENKTL). The secondary objectives were to determine response rates, survival outcomes, prognostic factor for overall survival (OS), and validation of the Prognostic Index of Natural Killer Lymphoma (PINK), Ann Arbor staging system (AASS), and the CA system. : This retrospective study included data pertaining to patients with newly diagnosed ENKTL in Chiang-Mai University Hospital from 2004 to 2020.
View Article and Find Full Text PDFFunctional Septorhinoplasty in Unilateral and Bilateral Nasal Obstruction: A Comparison of Patient-Reported Outcomes.
Ann Otol Rhinol Laryngol
December 2024
Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, OR, USA.
Purpose: Functional septorhinoplasty is an effective treatment for nasal airway obstruction. Little distinction exists between bilaterally and unilaterally obstructed patients in literature. Our study evaluates outcomes in patients with unilateral nasal airway obstruction compared to those with bilateral nasal airway obstruction as measured by nasal obstruction symptom evaluation scores following functional septorhinoplasty.
View Article and Find Full Text PDFNasal Obstruction Outcomes in Medial Flap Turbinoplasty and Inferior Turbinate Submucous Resection.
Laryngoscope
December 2024
Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, Orange, California, U.S.A.
Objectives: To compare longitudinal improvement in nasal obstruction quality-of-life outcomes between medial flap turbinoplasty (MFT) and inferior turbinate submucous resection (SMR) concurrently performed with functional septorhinoplasty.
Methods: Retrospective review of a prospectively collected cohort of patients undergoing functional septorhinoplasty between 2015 and 2022 at a tertiary academic center. Outcomes were assessed using the Nasal Obstruction Symptom Evaluation (NOSE) questionnaire preoperatively and over 12 months postoperatively.
Comparison of Nasal Packing, Trans-septal Suturing, and Submucosal Trans-septal Suturing Techniques After Septal Extension Grafts With Autogenous Costicartilage.
J Craniofac Surg
December 2024
Department of Plastic Surgery, the Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University.
Background: Nasal packing (NP), trans-septal suturing (TSS), and submucosal trans-septal suturing (STSS) are common techniques to avoid dead space after the deviated septum is corrected. However, there is rare data about surgical complications and discomfort of these techniques after septal extension grafts (SEG) with autogenous costicartilage.
Objective: To compare the complications and discomfort of NP, TSS, and STSS techniques after SEG with autogenous costicartilage.
Impact of Preoperative Lacrimal Sac Morphology on Postoperative Rhinostomy Shape and Prognosis in Endoscopic Dacryocystorhinostomy.
J Craniofac Surg
December 2024
Konkuk University School of Medicine, Chungju City, Republic of Korea.
Purpose: To determine the association between the preoperative shape of the lacrimal sac and the postoperative shape of a rhinostomy in patients undergoing endoscopic dacryocystorhinostomy (DCR) for primary acquired nasolacrimal duct obstruction.
Material And Methods: This retrospective study involved 180 cases among 129 patients. Preoperative dacryocystography (DCG) classified lacrimal sacs into constricted or cylindrical types based on their width relative to the nasolacrimal duct.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!