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Survival of HIV associated diffuse large B-cell lymphoma and Burkitt lymphoma in China.
Sci Rep
December 2024
Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, 430071, China.
Article Synopsis
- Combination antiretroviral therapy (ART) has significantly improved the treatment outcomes for patients with HIV-associated non-Hodgkin lymphoma, specifically Burkitt lymphoma and diffuse large B-cell lymphoma, based on a study of 127 patients treated over 17 years.
- The study found that DA-EPOCH ± R was the most common therapy for HIV-BL, while CHOP± R was used for HIV-DLBCL, with complete response rates of 36% and 44%, respectively.
- Despite these advancements, challenges remain in treating HIV-related lymphomas in China due to low rates of pre-diagnosis ART, high patient morbidity, and late-stage diagnoses.
A rare case of pulmonary cryptosporidiosis associated with pulmonary tuberculosis in a patient with advanced HIV infection.
Parasitol Int
February 2025
Clinical Hospital of Infectious Diseases of Cluj-Napoca, 23 Iuliu Moldovan, 400348 Cluj-Napoca, Romania; Department of Infectious Diseases and Epidemiology, "Iuliu Hațieganu" University of Medicine and Pharmacy, 23 Iuliu Moldovan, 400348 Cluj-Napoca, Romania.
Cryptosporidium spp., an important food and waterborne protozoan pathogen, can cause severe diarrhea and extraintestinal manifestations in immunocompromised individuals. The case of a 75 -years old patient diagnosed as a late presenter with advanced HIV infection and multiple opportunistic illnesses associated to HIV: cryptosporidiosis, intestinal and pulmonary, Cytomegalovirus colitis and pulmonary tuberculosis is presented.
View Article and Find Full Text PDFAmoebic colitis in a 39-year-old man with HIV.
CMAJ
September 2024
Department of Infectious Diseases, Tokyo Metropolitan Toshima Hospital, Tokyo, Japan.
Molecular identification and genetic characteristics of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in human immunodeficiency virus/acquired immunodeficiency syndrome patients in Shanghai, China.
Parasit Vectors
February 2023
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, 200025, Shanghai, China.
Background: Opportunistic infections are a ubiquitous complication in human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients. Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi are common opportunistic intestinal pathogens in humans.
View Article and Find Full Text PDFFollow-Up to High-Resolution Anoscopy After Abnormal Anal Cytology in People Living with HIV.
AIDS Patient Care STDS
July 2022
Office of the Senior Vice President of Research, Emory University, Atlanta, Georgia, USA.
Current expert recommendations suggest anal cytology followed by high-resolution anoscopy (HRA) for biopsy and histological confirmation may be beneficial in cancer prevention, especially in people living with HIV (PLWH). Guided by the social ecological model, the purpose of this study was to examine sociodemographic and clinical variables, individual-level factors (depression, HIV/AIDS-related stigma, and health beliefs) and interpersonal-level factors (social support) related to time to HRA follow-up after abnormal anal cytology. We enrolled 150 PLWH from a large HIV community clinic, with on-site HRA availability, in Atlanta, GA.
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