Background: Anemia, especially due to iron deficiency early in pregnancy, has adverse consequences on pregnancy outcomes.
Methods: A cross-sectional study of 480 pregnant women in their second trimester was conducted in Senegal's capital, Dakar. Eighty women were selected per health center. Parasitological, dietary, and genetic factors were assessed to ascertain their relationship to anemia status and etiology.
Results: Thirty-nine percent of the women were anemic; only 12-13% of the women had any parasite. Daily heme iron was reported in 35% of women, but intake amounts were low. Intakes of iron inhibitors were frequently consumed. Mean hemoglobin and serum ferritin levels were significantly higher and erythrocyte protoporphyrin levels were lower in women who consumed iron inhibitors less frequently.
Conclusions: Results of this study can improve the current antenatal program in Senegal and similar West African countries. Educating about dietary iron inhibitors and encouraging patient compliance can be significant contributors to reducing anemia in pregnancy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/09637480903348114 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Anti-ferroptotic effects of natural polyphenols in nervous system injury: a narrative literature review.
Nutr Neurosci
January 2025
Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Background: Recent studies have shown that ferroptosis, a newly identified regulated cell death characterized by increased lipid peroxidation and accumulation of toxic lipid peroxides, is closely related to the pathophysiological processes of nervous system diseases which can be inhibited with iron chelators, lipophilic antioxidants, and lipid peroxidation inhibitors.
Objective: To review the current evidence on the efficacy of various natural polyphenols in nervous system injury.
Methods: The data selected for this review were collected by searching the MEDLINE/PubMed, Web of Science, Scopus, and Google Scholar database for articles published in English between 2000 and 2024 using the following terms: cell death, regulated cell death, ferroptosis, lipid peroxides, iron, and glutathione peroxidase.
Three-Dimensional SERS-Active Hydrogel Microbeads Enable Highly Sensitive Homogeneous Phase Detection of Alkaline Phosphatase in Biosystems.
ACS Appl Mater Interfaces
January 2025
State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China.
Alkaline phosphatase (ALP) is a biomarker for many diseases, and monitoring its activity level is important for disease diagnosis and treatment. In this study, we used the microdroplet technology combined with an laser-induced polymerization method to prepare the Ag nanoparticle (AgNP) doped hydrogel microbeads (HMBs) with adjustable pore sizes that allow small molecules to enter while blocking large molecules. The AgNPs embedded in the hydrogel microspheres can provide SERS activity, improving the SERS signal of small molecules that diffuse to the AgNPs.
View Article and Find Full Text PDFAbsence of Cysteine and Iron Chelation Induces Ferroptosis in Triple-Negative Breast Cancer Cells.
Breast Cancer (Auckl)
January 2025
Department of Pharmacy, Yonsei University, Incheon, South Korea.
Background: Ferroptosis is a recently studied form of programmed cell death characterized by lipid peroxides accumulation in the cells. This process occurs when a cell's antioxidant capacity is disturbed resulting in the inability of the cell to detoxify the toxic peroxides. Two major components that regulate ferroptosis are cysteine and iron.
View Article and Find Full Text PDFModulating Ferroptosis: A Novel Approach to Promote Neural Repair in Brain Injury.
Curr Neuropharmacol
January 2025
College of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
The increasing prevalence of brain injuries resulting in cognitive and motor function impairments poses a substantial global medical challenge. Nerve repair therapies offer promise for addressing brain injury-related disorders. Ferroptosis, as a cell death mechanism associated with oxidative stress and inflammation.
View Article and Find Full Text PDFCombined Toxicity Assessment of Deoxynivalenol and Pb on HK-2 Cells Involved in Excessive ROS-Induced Ferroptosis.
J Agric Food Chem
January 2025
Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, 1000 Jingqi Road, Shanghai 201403, China.
The cocontamination of food by several mycotoxins and heavy metals poses significant health risks, and their combined toxic effects remain poorly understood. Particularly, specific studies exploring their combined impact on ferroptosis remain limited. In this work, we investigated the combined toxic effects of a mycotoxin, called deoxynivalenol (DON), and a heavy metal, called plumbum (Pb), and explored the potential mechanisms of DON and Pb co-occurrence via excessive ROS-induced ferroptosis in HK-2 cells.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!