The Resident Assessment Instrument/Minimum Data Set (RAI/MDS) is the foundational clinical framework for nursing home care, functioning as both a clinical assessment instrument and an assessment process. An RN is mandated by statute to complete or coordinate the work associated with this framework. Using both focus groups and questionnaires, 24 RN MDS coordinators attending a national conference for MDS coordinators described their work in its organizational context. Shortell et al.'s continuous quality framework of structural, technical, cultural, and strategic organizational dimensions was used to categorize descriptive themes. Clinical implications of the study findings are summarized.
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http://dx.doi.org/10.3928/19404921-20080101-04 | DOI Listing |
ACS Sens
December 2024
Electronics and Telecommunications Research Institute (ETRI), Daejeon 34129, Republic of Korea.
The increasing prevalence of obesity and metabolic disorders has created a significant demand for personalized devices that can effectively monitor fat metabolism. In this study, we developed an advanced breath analyzer system designed to provide real-time monitoring of exercise-induced fat burning by analyzing volatile organic compounds (VOCs) present in both oral and alveolar breath. Acetone in exhaled breath and β-hydroxybutyric acid (BOHB) in the blood are both biomarkers closely linked to the metabolic fat burning process occurring in the liver, particularly after exercise.
View Article and Find Full Text PDFJ Phys Chem B
December 2024
Centro de Química Estrutural, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.
This study addresses a critical gap in the existing literature on carbon dioxide and ionic liquid (IL) mixtures, where fragmented and incomplete data, particularly for flow properties, hinder practical applications. Therefore, this work aimed to establish a robust and efficient method for predicting the density of the CO-IL mixtures across diverse operating conditions and IL families using novel validation techniques. Both linear and symbolic regression models provided relevant insights but failed to accurately capture the IL-CO interactions in a mixture that determine the molar volume of CO at infinite dilution when solubilized by a given IL.
View Article and Find Full Text PDFPhys Ther
December 2024
Leni and Peter W. May Department of Orthopaedics and Institute for Healthcare Delivery Science, Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Objective: Prehabilitation may have benefits for total hip arthroplasty (THA) and total knee arthroplasty (TKA), given an aging population with multimorbidity and the growth of value-based programs that focus on reducing postoperative costs. We aimed to describe prehabilitation use and examine predictors of utilization in fee-for-service Medicare beneficiaries.
Methods: This retrospective cohort study using the Medicare Limited Data Set included fee-for-service Medicare beneficiaries who were ≥ 66 years old and who underwent inpatient elective THA or TKA between January 1, 2016, and September 30, 2021.
Anal Chem
December 2024
MOBILion Systems, Chadds Ford, Pennsylvania 19317, United States.
Rapid identification of asparagine (Asn) deamidation and isoaspartate (Asp) in proteins remains a challenging analytical task during the development of biological therapeutics. For this study, 46 therapeutically relevant peptides corresponding to 13 peptide families (13 unmodified peptides and 33 modified peptides) were obtained; modified peptides included Asn deamidation and isoAsp. The peptide families were characterized by three methods: reversed-phase ultrahigh performance liquid chromatography-mass spectrometry (RP-UHPLC-MS); flow injection analysis high-resolution ion mobility-mass spectrometry (FIA-HRIM-MS); and shortened gradient RP-UHPLC-HRIM-MS.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Neurology, University of Kansas School of Medicine, Kansas City, Kansas, USA.
Introduction: TOMM40 and APOC1 variants can modulate the APOE-ε4-related Alzheimer's disease (AD) risk by up to fourfold. We aim to investigate whether the genetic modulation of ε4-related AD risk is reflected in brain morphology.
Methods: We tested whether 27 magnetic resonance imaging-derived neuroimaging markers of neurodegeneration (volume and thickness in temporo-limbic regions) are associated with APOE-TOMM40-APOC1 polygenic profiles using the National Alzheimer's Coordinating Center Uniform Data Set linked to the AD Genetic Consortium data.
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