Objectives: To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group.
Methods: The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin-embedded tissue sections.
Results: The immunohistochemical reaction produced by the anti-HER-2/Neu antibody was positive in two cases (5.4%).
Conclusion: The low prevalence of Her-2/Neu observed in these southern brazilian cases is probably due to the great number of poorly differentiated cancers in this series.
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| http://dx.doi.org/10.1590/s0100-69912009000200007 | DOI Listing |
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