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Prenatal hair development: implications for drug exposure determination. | LitMetric

Prenatal hair development: implications for drug exposure determination.

Forensic Sci Int

Division of Clinical Pharmacology & Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.

Published: March 2010

AI Article Synopsis

  • Neonatal hair is a valuable tool for identifying drug exposure during pregnancy, making it important in toxicology.
  • The paper reviews how hair follicles develop and produce hair while in the womb.
  • Understanding the timing and mechanisms of hair development helps experts accurately determine when a fetus might have been exposed to harmful substances.

Article Abstract

Neonatal hair is a clinically important toxicological matrix, as it allows determination of in utero drug exposure. This paper serves to review the physiological development of the hair follicle and hair production during fetal life. An understanding of the mechanisms and timing of hair development in the prenatal period is critical to effectively assessing the time window of exposure determination associated with toxicological analysis of neonatal hair.

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Source
http://dx.doi.org/10.1016/j.forsciint.2009.12.024DOI Listing

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