A 54-year-old Japanese man without underlying disease developed pneumococcal bacteremia and meningitis after traveling to the Philippines. The isolate demonstrated high affinity to the lung and invasiveness in vivo. The international travelers can import indigenous high virulent strains even if the bacterium is commonly isolated in the home country.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1708-8305.2009.00377.xDOI Listing

Publication Analysis

Top Keywords

invasive pneumococcal
4
pneumococcal disease
4
disease traveler
4
traveler returned
4
returned philippines
4
philippines case
4
case report
4
report vivo
4
vivo study
4
study isolate
4

Similar Publications

Introduction: Pneumococcal diseases (PD) caused by include invasive PD (IPD) and non-bacteremia pneumococcal pneumonia (NBPP). Current French vaccination guidelines FOCUS on patients with underlying medical conditions (UMC) who are at a higher risk of PD. This study describes the healthcare resource utilization (HCRU) and economic burden of inpatient PD in French adults, to inform vaccination guidelines, especially among vulnerable subpopulations at increased risk of PD.

View Article and Find Full Text PDF

Background: Due to high costs of pneumococcal conjugate vaccines (PCV), transitioning from a two (2 + 1) to a single dose (1 + 1) primary series with a booster should be considered. This study evaluated the immune response at 18 months of age following a 1 + 1 compared to a 2 + 1 schedule of 10-valent (PCV10) and 13-valent (PCV13) vaccines.

Research Design And Methods: A single-center, open-label, randomized trial conducted in Soweto, South Africa, evaluated the immunogenicity of differing dosing schedule for PCV10 and PCV13.

View Article and Find Full Text PDF

Background: Pneumococcal conjugate vaccines (PCVs) introduced in childhood national immunization programs lowered vaccine-type invasive pneumococcal disease (IPD), but replacement with non-vaccine-types persisted throughout the PCV10/13 follow-up period. We assessed PCV10/13 impact on pneumococcal meningitis incidence globally.

Methods: The number of cases with serotyped pneumococci detected in cerebrospinal fluid and population denominators were obtained from surveillance sites globally.

View Article and Find Full Text PDF

In this study, we describe S. pneumoniae serotype distribution before and after PCV13 rollout in Tanzania. We serotyped S.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!