The degradation of natural resources is increasing in alarming numbers, especially water sources that is constant changes in its quality. Because of this, more and more people come using groundwater for human consumption, but the big problem is contamination by these pathogenic microorganisms. The purpose of this study was to evaluate the microbiological quality of groundwater districts in the Extreme West of Santa Catarina, Brazil. We analyzed 149 samples of water from wells in 14 municipalities during the period January 2005 to December 2006. Were determined in all samples the total coliform and thermotolerant. The results showed high rates of samples inappropriate for consumption, with 54.7% in 2005 and 56.7% in 2006. Our data show the risk of diseases spreading of water that the region's population is exposed to the consumption of water, showing a serious public health problem.
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http://dx.doi.org/10.1590/s1413-81232009000600027 | DOI Listing |
Animals (Basel)
December 2024
Center for Exceptional Longevity Studies, Gerald P. Murphy Cancer Foundation, West Lafayette, IN 47906, USA.
Frailty refers to a state of increased vulnerability to mortality and other adverse outcomes as a consequence of age-related decline in physiologic reserve and function. Comparative biomedical scientists are relied upon to innovate approaches to enhance understanding of the similarities and differences between humans and other animal species that can impact healthy aging. The research aim of this study was to develop a clinical frailty index (FI) in the Exceptional Aging in Rottweilers Study (EARS) and test its ability to predict all-cause mortality in elderly dogs.
View Article and Find Full Text PDFFront Genet
December 2024
Department of Pediatrics, West China Second University Hospital, Chengdu, Sichuan, China.
Background: Autosomal recessive cutis laxa type 1B (ARCL1B) is an extremely rare disease characterized by severe systemic connective tissue abnormalities, including cutis laxa, aneurysm and fragility of blood vessels, birth fractures and emphysema. The severity of this disease ranges from perinatal death to manifestations compatible with survival. To date, no cases have been reported in the Chinese population.
View Article and Find Full Text PDFSci Rep
January 2025
Shandong Provincial Key Laboratory of Depositional Mineralization & Sedimentary Minerals, College of Earth Science & Engineering, Shandong University of Science and Technology, No.579, Qianwangang Road, West Coast New Economic District, Qingdao, 266590, Shandong, China.
Coal-burning fluorosis prevails in southwest China and other provinces. Although clay used as binder of briquettes was proven to cause coal-burning fluorosis, its enrichment processes remain unknown. The soils and rocks on typical geological units were sampled and simulation experiments were performed to detect the forming process of high-fluoride clay.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Department of Cardiothoracic Surgery, The First People's Hospital of Neijiang, No. 1866, West Section of Hanan Avenue, Shizhong District, Neijiang, Sichuan, 641000, P.R. China.
Background: Primary mediastinal liposarcomas (PLMs) are extremely rare. Patients typically present with symptoms caused by tumor size, as the mass can compress surrounding tissues and organs. Here, we report a case of a large primary mediastinal liposarcoma that was successfully resected thoracoscopically.
View Article and Find Full Text PDFEur J Med Chem
December 2024
Department of Neurology, Laboratory of Neuro-system and Multimorbidity, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. Electronic address:
Covalent inhibitors provide persistent inhibition while maintaining excellent selectivity and efficacy by creating stable covalent connections with specific amino acids in target proteins. This technique enables the precise inhibition of previously undruggable targets, lowering the frequency of administration and potentially bypassing drug resistance. Because of these advantages, covalent inhibitors have tremendous potential in treating cancer, inflammation, and infectious illnesses, making them extremely important in modern pharmacological research.
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