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The most important prognostic factors for predicting major adverse cardiovascular, cerebrovascular, and renal events during 5-year follow-up of patients with chronic kidney disease with or without haemodialysis.
Nucl Med Commun
January 2025
Division of Cardiology, Onishi Hospital, Fujioka, Japan.
Objective: Patients with chronic kidney disease (CKD) have an increased risk of adverse cardio-cerebrovascular events. The purpose of this study is to evaluate the prognostic predictors over 5 years in patients with CKD including haemodialysis.
Methods: In this multicenter, prospective cohort study performed with the Gunma-CKD SPECT Study protocol, 311 patients with CKD [estimated glomerular filtration rate (eGFR) < 60 min/ml/1.
Cerebral blood flow and arterial responses in migraine: history and future perspectives.
J Headache Pain
December 2024
Translational Research Center and Danish Headache Center, Rigshospitalet, University of Copenhagen, Nordstjernevej 42, Glostrup, Copenhagen, 2600, Denmark.
Article Synopsis
- The text examines the historical and contemporary research surrounding migraine with aura (MA) and migraine without aura (MO), highlighting how they differ in terms of their underlying mechanisms related to cortical spreading depression (CSD).
- The review draws on extensive literature and past studies, particularly emphasizing evidence from 133-Xenon studies that illustrate changes in cerebral blood flow (rCBF) during MA and challenge the previously accepted vasospastic theory of migraine.
- It suggests that while modern imaging techniques have confirmed and expanded upon earlier findings, a definitive study to conclusively determine the role of CSD in MA versus MO is still needed.
Research progress in tracing technology for extracellular vesicles.
Extracell Vesicles Circ Nucl Acids
December 2023
School of Bioscience and Technology, Weifang Medical University, Weifang 261053, Shandong, China.
Cells have the capability to discharge extracellular vesicles (EVs) into a range of bodily fluids. Extracellular vesicles (EVs) encapsulate biological molecules such as proteins and nucleic acids, playing a role in facilitating cell-cell communication. They actively engage in a myriad of physiological and pathological processes.
View Article and Find Full Text PDFImpact of perioperative cerebral blood flow evaluation using arterial spin labeling in a patient undergoing carotid artery stenting.
J Clin Neurosci
December 2024
Department of Neurosurgery, Gifu Medical University, 1-1 Yanagido, Gifu City, Gifu, Japan.
Background: Hyperperfusion syndrome (HPS) is one of the most serious complications after carotid artery stenting (CAS). Arterial spin labeling (ASL) is a noninvasive method for assessing cerebral perfusion. This study aimed to evaluate the utility of ASL compared to that of SPECT in evaluating changes in intracranial blood flow during the perioperative period of CAS.
View Article and Find Full Text PDFNeuropsychological performances and brain perfusion patterns in patients with first episode psychosis.
J Psychiatr Res
January 2025
Department of Psychiatry, School of Health Sciences, Faculty of Medicine, University of Ioannina, Greece. Electronic address:
Abnormalities in cognition are a pronounced feature in primary psychotic disorders and may appear long before the manifestation of the first-episode psychosis (FEP). Although brain functional changes may precede structural alterations, brain perfusion patterns in FEP and most importantly their correlations with cognition remain poorly understood. In the present study we assessed neurocognitive functions and regional cerebral blood flow (rCBF) in 53 patients with a diagnosis of FEP.
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