Department of Physical and Astronomical Sciences, University of Palermo, via Archirafi 36, I-90123 Palermo, Italy.
Published: February 2010
AI Article Synopsis
Article Abstract
Elastic incoherent neutron scattering has been used to study the temperature dependence of the mean-square displacements of nonexchangeable hydrogen atoms in powders of a series of homomeric polypeptides (polyglycine, polyalanine, polyphenylalanine and polyisoleucine) in comparison with myoglobin at the same hydration level (h = 0.2). The aim of the work was to measure the dynamic behavior of different amino acid residues separately and assess the contribution of each type of side chain to the anharmonic dynamics of proteins. The results provide direct experimental evidence that the first anharmonic activation, at approximately 150 K, is largely due to methyl group rotations entering the time window of the spectrometer used; however, contributions on the order of 10-20% from the motions of other groups (e.g., the phenolic ring and the methylene groups) are present. Our data also indicate that the dynamical transition occurring at approximately 230 K can be attributed, at least at the hydration level investigated, mainly to motions involving backbone fluctuations.
Research Group in Bioclimatology, Ethology and Animal Welfare (BioEt), Department of Animal Science, Federal University of Paraiba, Areia, Paraiba, Brazil.
The present study aimed to evaluate the effects of different nutritional plans on meat quails subjected to heat stress. A total of 324 quails male European quails () were used, with an average initial weight of 121.48 g ± 3.
Chronic wounds in diabetic patients experience significant clinical challenges due to compromised healing processes. Hypoxia-inducible factor-1 alpha (HIF-1α) is a critical regulator in the cellular response to hypoxia, enhancing angiogenesis and tissue restoration. Nevertheless, the cellular response to the developed chronic hypoxia within diabetes is impaired, likely due to the destabilization of HIF-1α via degradation by prolyl hydroxylase domain (PHD) enzymes.
Introduction: Strains of the syphilis spirochete, ssp. , group into one of two deep-branching clades: the Nichols clade or the globally dominant Street Strain 14 (SS14) clade. To date, in-depth proteome-wide analyses have focused on Nichols clade strains.
Introduction: Hyperuricemia (HUA) refers to the presence of excess uric acid (UA) in the blood, which increases the risk of chronic kidney disease and gout. Probiotics have the potential to alleviate HUA.
Methods: This study established a hyperuricemia model using (), and studied the anti-hyperuricemia activity and potential mechanisms of BC99 () at different concentrations (10 CFU/mL BC99, 10 CFU/mL BC99).
