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Alaska's Flora as a Treatment for Cancer.
Int J Biopharm Sci
December 2024
Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham NH 03824.
Cancer is an extraordinarily complex illness, with many tumors ultimately developing resistance to the currently available therapeutics. This highlights a need for the discovery of new anticancer medicines. Natural products have been utilized for centuries by the indigenous people of Alaska for both spiritual and medicinal purposes and have traditionally been administered as medicine for a wide range of ailments from the common cold to cancer.
View Article and Find Full Text PDFIndirect effect of psychological capital by using Partial Least Square (PLS) path analysis.
MethodsX
June 2025
School of Social Sciences and Languages, Vellore Institute of Technology, Chennai, India.
Understanding the relationship between Learned Helplessness (LH) and Psychological Capital (PsyCap) is essential for developing effective interventions for Indigenous adolescents. This study explored the role of PsyCap as a mediator in the link between LH and Psychological Well-Being (PWB). Total of 173 Indigenous adolescents (85 boys and 88 girls) from sixth to eleventh grade at government residential schools.
View Article and Find Full Text PDFImpact of Policy Changes Expanding Access to Direct-Acting Antivirals on Hepatitis C Virus-Related Hospitalizations in People With HIV: A Population-Based Study.
Open Forum Infect Dis
January 2025
Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Ontario, Canada.
Background: The burden of hepatitis C virus (HCV)-related hospitalizations is substantial, particularly among people with HIV and HCV. In Ontario, Canada, use of direct-acting antivirals (DAAs) increased following policies removing fibrosis-stage restrictions and approving of pangenotypic agents in 2017 and 2018, respectively. We examined the impact of expanded DAA access on HCV-related hospitalizations in people with HIV.
View Article and Find Full Text PDFLong-term 4CMenB Vaccine Effectiveness Against Gonococcal Infection at Four Years Post-Program Implementation: Observational Case-Control Study.
Open Forum Infect Dis
January 2025
Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, Adelaide, South Australia, Australia.
Background: A 4-component meningococcal B (4CMenB) vaccine program was introduced in adolescents in 2019 in South Australia. We aimed to evaluate long-term vaccine effectiveness (VE) and impact (VI) on gonococcal infection 4 years after implementation of the program.
Methods: Disease notification data were provided by SA Health.
The sense of safety theoretical framework: a trauma-informed and healing-oriented approach for whole person care.
Front Psychol
January 2025
School of Population Health, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
Objectives: This research describes four aspects of the development of the Sense of Safety Theoretical Framework for whole person care: exploring the meaning of the phrase "sense of safety"-the whole person ; the range of human experience that impacts sense of safety-whole person ; the dynamics that build sense of safety-the healing ; and the personal and cross-disciplinary trauma-informed practitioner that facilitate sense of safety.
Methods: This qualitative participatory study was conducted in two phases. Researchers iteratively explored the concept of sense of safety using focus groups and semi-structured interviews.
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