Objective: The goal was to describe the mental and physical health of caregivers and the home environments of children who have been investigated by child protective services (CPS).
Methods: Subjects were 5299 children 0 to 14 years of age, from the National Survey of Child and Adolescent Well-being, a cohort study of children investigated by CPS. The Short-Form Health Survey was used to measure mental and physical health. The Home Observation for Measurement of the Environment-Short Form (HOME-SF) total and cognitive stimulation subscale scores were used to measure developmentally appropriate characteristics of children's home environments. These validated measures were compared across placement types, that is, remaining at home (investigated home), nonrelative foster care (foster care), and relative foster care (kin care).
Results: Kin and foster caregivers had better-than-average mental health, but 11% to 13% of kin/foster caregivers and 24% of investigated-home caregivers had scores consistent with untreated mental illness. All caregivers had worse-than-average physical health; 25% of foster and 26% of kin caregivers had scores consistent with serious physical illness. There was no significant difference in mean HOME-SF scores between foster and investigated homes. Kin care homes of 6- to-10-year-old children were superior to investigated and foster homes. All setting types had more homes in the lowest quartile than in the highest quartile for HOME-SF and cognitive stimulation subscale scores.
Conclusions: A sizable minority of children investigated by CPS subsequently live in homes with mentally or physically ill caregivers and with developmentally inadequate nurturing and stimulation. Foster homes are indistinguishable from investigated homes on the HOME-SF. Clinicians should assess the mental and physical health of caregivers and should facilitate access to appropriate resources, including parent/caregiver training programs.
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http://dx.doi.org/10.1542/peds.2008-3814 | DOI Listing |
JAMA Pediatr
January 2025
Division of Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Importance: Cyclophosphamide and calcineurin inhibitors are the most used nonsteroid immunosuppressive medications globally for children with various chronic inflammatory conditions. Their comparative effectiveness remains uncertain, leading to worldwide practice variation. Nephrotic syndrome is the most common kidney disease managed by pediatricians globally and suboptimal treatment is associated with high morbidity.
View Article and Find Full Text PDFJ Autism Dev Disord
January 2025
Institutes for Behavior Resources, Inc, 2104 Maryland Ave., Baltimore, MD, 21218, USA.
We aimed to compare sleep problems in autistic and non-autistic adults with co-occurring depression and anxiety. The primary research question was whether autism status influences sleep quality, after accounting for the effects of depression and anxiety. We hypothesized that autistic adults would report higher levels of depression, anxiety, and sleep problems compared to non-autistic adults, after controlling for these covariates.
View Article and Find Full Text PDFJ Gerontol B Psychol Sci Soc Sci
January 2025
Ryan White Center for Pediatric Infectious Diseases and Global Health, Indiana University School of Medicine. Indianapolis, Indiana, USA.
Objectives: The rise in gray divorce has catalyzed repartnering in later life. However, the antecedents of older adult repartnering remain poorly understood, particularly the potential role of adult children. A form of ambiguous loss, marital disruption often leads to family boundary ambiguity, thereby weakening family ties.
View Article and Find Full Text PDFEur J Clin Invest
January 2025
Second Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) commonly leads to heart failure but has traditionally been an exclusion criterion in randomized clinical trials (RCTs) of sodium-glucose cotransporter 2 inhibitors (SGLT2i); therefore, the effects of these drugs in this population remain undocumented. In light of recent studies, this meta-analysis aimed to investigate the effect of SGLT2i on the prognosis of patients with ATTR-CM.
Methods: A comprehensive search of Medline, Scopus, and the Cochrane Library was conducted up to November 17, 2024.
Clin Pharmacol Ther
January 2025
Department of Pharmacology, Center for Pharmacogenomics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Clopidogrel, an anti-platelet drug, is used to prevent thrombosis after percutaneous coronary intervention. Clopidogrel resistance results in recurring ischemic events, with African Americans (AA) suffering disproportionately. The aim of this study was to discover novel biomarkers of clopidogrel resistance in African Americans using genome and transcriptome data.
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