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Background: Vaccination of farmed salmonids has been an integral part of preventing infectious diseases in Norway's aquaculture industry. In Norway, vaccine usage is regulated by the government. There is a need to monitor vaccine usage for both regulatory and research purposes, at local and national scales.

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A Machine Learning Model to Harmonize Volumetric Brain MRI Data for Quantitative Neuroradiological Assessment of Alzheimer Disease.

Radiol Artif Intell

December 2024

From the Laboratory of Neuroinformatics, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Via Pilastroni 4, Brescia 25125, Italy (D.A., A.R.); Department of Neurology, Alzheimer Center Amsterdam, Vrije Universiteit, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands (V.V., W.M.v.d.F., B.M.T.); Department of Neurodegeneration, Amsterdam Neuroscience, Amsterdam, the Netherlands (V.V., W.M.v.d.F., B.M.T.); Brain Imaging Centre, Research Centre for Natural Sciences, Budapest, Hungary (B.W., T.A., Z.V.); Biomatics and Applied Artificial Intelligence Institute, John von Neumann Faculty of Informatics, Óbuda University, Budapest, Hungary (B.W.); Department of CSIRO Health and Biosecurity, The Australian e-Health Research Centre, Brisbane, Australia (P.B.); School of Psychology, University of Surrey, Guildford, United Kingdom (T.A.); Sorbonne Université, Institut du Cerveau- Paris Brain Institute-ICM, CNRS, Inria, Inserm, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France (S.D.); Department of Epidemiology and Data Science, Vrije Universiteit, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands (W.M.v.d.F.); Department of Radiology & Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, Amsterdam the Netherlands (F.B.); Queen Square Institute of Neurology, University College London, United Kingdom (F.B.); and UCL Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering and Department of Computer Science, University College London, London, United Kingdom (F.B., D.C.A., A.A., N.P.O.).

Purpose To extend a previously developed machine learning algorithm for harmonizing brain volumetric data of individuals undergoing neuroradiological assessment of Alzheimer disease not encountered during model training. Materials and Methods Neuroharmony is a recently developed method that uses image quality metrics (IQM) as predictors to remove scanner-related effects in brain-volumetric data using random forest regression. To account for the interactions between Alzheimer disease pathology and IQM during harmonization, the authors developed a multiclass extension of Neuroharmony for individuals with and without cognitive impairment.

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Article Synopsis
  • - One Health (OH) is a strategy aimed at improving the health of humans, animals, and ecosystems together, particularly to tackle issues like antimicrobial resistance (AMR) with a comprehensive approach.
  • - A scoping review of literature on antibiotic-resistant Escherichia coli in Africa revealed that most research was concentrated in Eastern Africa, highlighting a significant gap in data for many countries and identifying the food chain as a key transmission route.
  • - The review calls for increased focus on antimicrobial stewardship, hygiene, and biosecurity practices, alongside AMR surveillance and OH-driven research to promote the overall health of humans, animals, and the environment.
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The 2024 Zebrafish Husbandry Workshop and Summit held during the World Aquaculture Society Meeting in San Antonio focused on key areas for improving zebrafish husbandry research. Discussions highlighted the need for comprehensive literature on husbandry, better communication and collaboration between researchers and facility staff, and the adoption of a standardized reference diet. Current literature lacks comprehensive data and often overlooks crucial factors such as housing density and space requirements for fish development.

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Southeast Asian countries are at the forefront of public health pressures due to a confluence of factors such as population growth, urbanization, environmental pollution, and infectious diseases (re)emergence. Therefore, the ability to be able to conduct research addressing local and regional needs is of paramount importance. As such, biobanking activities, the standardized collection of biological samples, and associated data, developed over the past few decades supporting ongoing biomedical and clinical research, as well as surveillance are of critical importance.

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