An opening of vinyl oxiranes has been accomplished with Zn and Al enolates resulting from asymmetric conjugate addition reactions on cyclic enones. This novel tandem procedure affords the adducts in moderate to good yields, enantioselectivities up to 98%, and moderate to good cis/trans selectivities. This provides potentially useful synthetic substrates to prepare complex bicyclic compounds.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol9027682 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Electrochemical Performance of Guanidinium Salt-Added PVP/PEO Solid Polymer Electrolyte with Superior Power Density.
Polymers (Basel)
January 2025
School of Chemical Engineering, Yeungnam University, 280 Daehak-ro, Gyeongsan 38541, Republic of Korea.
Solid polymer electrolytes (SPEs) for symmetrical supercapacitors are proposed herein with activated carbon as electrodes and optimized solid polymer electrolyte membranes, which serve as the separators and electrolytes. We propose the design of a low-cost solid polymer electrolyte consisting of guanidinium nitrate (GuN) and poly(ethylene oxide) (PEO) with poly(vinylpyrrolidone) (PVP). Using the solution casting approach, blended polymer electrolytes with varying GuN weight percentage ratios of PVP and PEO are prepared.
View Article and Find Full Text PDFPhosphine-Catalyzed Cascade Cycloaddition of Vinyl Oxiranes with Sulfonium Compounds to Step-Economically Construct Spiro-2(3)-furanone Scaffolds.
Org Lett
January 2025
School of Pharmaceutical Sciences and Institute of Materia Medica, Medical Science and Technology Innovation Center, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P. R. China.
In this work, we developed a phosphine-catalyzed cascade lactonization/[2 + 1] annulation reaction between vinyl oxiranes and sulfonium compounds for the highly diastereoselective construction of spiro-2(3)-furanone skeletons. The cascade cycloaddition proceeds via the 2(5)-furanone phosphonium intermediate, introducing an oxygen-containing active intermediate for phosphine catalysis. These findings highlight the significant potential of harnessing vinyl oxiranes as versatile synthons for constructing spirocyclic compounds through simultaneous multicyclic skeleton formation.
View Article and Find Full Text PDFIn Situ Polymerization Electrospinning of Amine-Epoxy/Poly(vinyl alcohol) Nanofiber Webs for Direct CO Capture from the Air.
ACS Omega
December 2024
Faculty of Materials Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
Article Synopsis
- To achieve carbon neutrality by 2050, capturing carbon dioxide from the atmosphere is essential, and direct air capture (DAC) using amine-based compounds is being researched for effectiveness.
- Researchers developed thermosetting DAC nanofibers that show strong performance with low-temperature desorption and heat resistance by polymerizing amines with epoxy, using poly(vinyl alcohol) (PVA) for easier fabrication.
- The resulting nanofiber webs demonstrated high CO adsorption capacity and efficient desorption, allowing for sustainable and low-energy recovery of CO while also maintaining stability over prolonged use.
Construction of 4-Vinyl-1,2-oxaphospholane 2-Oxides from Vinyloxiranes and Phosphoryl Diazomethanes.
Org Lett
January 2025
State Key Laboratory of Chemical Resource Engineering, Department of Organic Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, China.
Various 4-vinyl-1,2-oxaphospholane 2-oxides are prepared in good to excellent yields from vinyloxiranes and in situ-generated phosphenes from phosphoryl diazomethanes via the phosphene-induced ring expansion of oxiranes. The reaction is a novel and expeditious strategy for the synthesis of 1,2-oxaphospholane 2-oxide derivatives, featuring ring expansion of readily available starting materials, high atom economy, no catalyst, a fast reaction rate, broad functional group tolerance, high yields, and separable diastereomers.
View Article and Find Full Text PDFPioneering high barrier packaging for pressure assisted thermal sterilization of low-acid food products.
Food Res Int
November 2024
Department of Biological Systems Engineering, Washington State University, P.O. Box-646120, WA 99164-6120, USA. Electronic address:
Pressure-assisted thermal sterilization (PATS) utilizes flexible packaging with low oxygen and water vapor transmission rates (OTRs, WVTRs). In this study, pouches made from metal oxide (MO)-coated (A-D) and ethylene vinyl alcohol (EVOH)-containing (E, F) multilayer films were filled with water and mashed potatoes (MP), preheated at 98 ± 0.5 °C for 10 min, and processed using a pilot-scale high-pressure processing machine (HPP) at 600 ± 5 MPa for 300 s.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!