The paper describes an application of Bayes' Theorem to the problem of estimating from past data the probabilities that patients have certain diseases, given their symptoms. The data consist of hospital records of patients who suffered acute abdominal pain. For each patient the records showed a large number of symptoms and the final diagnosis to one of nine diseases or diagnostic groups. Most current methods of computer diagnosis use the "Simple Bayes" model in which the symptoms are assumed to be independent, but the present paper does not make this assumption. Those symptoms (or lack of symptoms) which are most relevant to the diagnosis of each disease are identified by a sequence of chi-squared tests. The computer diagnoses obtained as a result of the implementation of this approach are compared with those given by the "Simple Bayes" method, by the method of classification trees (CART), and also with the preliminary and final diagnoses made by physicians.
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Neuropsychol Rev
September 2023
Educational Testing Service, Foundational Psychometric and Statistical Research, 660 Rosedale Rd, M/s T-02, Princeton, NJ, 08541, USA.
Dr. Leonhard presents a comprehensive and insightful critique of the existing malingering research literature and its implications for neuropsychological practice. Their statistical critique primarily focuses on the crucial issue of diagnostic inference when multiple tests are involved.
View Article and Find Full Text PDFNeuropsychol Rev
September 2023
The Chicago School of Professional Psychology, Xavier University of Louisiana, New Orleans, USA.
The thoughtful commentaries in this volume of Drs. Bush, Jewsbury, and Faust add to the impact of the two reviews in this volume of statistical and methodological issues in the forensic neuropsychological determination of malingering based on performance and symptom validity tests (PVTs and SVTs). In his commentary, Dr.
View Article and Find Full Text PDFBioData Min
November 2022
Sharif University of Technology, Tehran, Iran.
Every year, the health of millions of people around the world is compromised by misdiagnosis, which sometimes could even lead to death. In addition, it entails huge financial costs for patients, insurance companies, and governments. Furthermore, many physicians' professional life is adversely affected by unintended errors in prescribing medication or misdiagnosing a disease.
View Article and Find Full Text PDFJ Digit Imaging
December 2019
Department of Electrical and Computer Engineering, Kharazmi University, Tehran, Iran.
Statistics show that the risk of autism spectrum disorder (ASD) is increasing in the world. Early diagnosis is most important factor in treatment of ASD. Thus far, the childhood diagnosis of ASD has been done based on clinical interviews and behavioral observations.
View Article and Find Full Text PDFTalanta
April 2016
CQE - Centro de Química Estrutural, Faculdade de Ciências da Universidade de Lisboa Edifício C8, Campo Grande, 1749-016 Lisboa, Portugal. Electronic address:
The identification of trace levels of compounds in complex matrices by conventional low-resolution gas chromatography hyphenated with mass spectrometry is based in the comparison of retention times and abundance ratios of characteristic mass spectrum fragments of analyte peaks from calibrators with sample peaks. Statistically sound criteria for the comparison of these parameters were developed based on the normal distribution of retention times and the simulation of possible non-normal distribution of correlated abundances ratios. The confidence level used to set the statistical maximum and minimum limits of parameters defines the true positive rates of identifications.
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