Heterotopic ossification represents one of the most frequent complications following any type of hip arthroplasty. However, disagreement exists regarding the clinical significance of heterotopic ossification after total hip arthroplasty (THA). This study evaluated the effect of different grades of heterotopic ossification on range of hip motion, pain, and the clinical outcome in patients after THA. The study included 198 patients with primary THA because of unilateral hip osteoarthritis, followed for a minimum of 1 year after THA. Diagnosis and classification of heterotopic ossification according to Brooker was achieved on anteroposterior radiograph of the hips 1 year postoperatively. The clinical outcome was assessed at 1-year follow-up with the use of the Harris hip score. Pain was assessed as the pain component of the Harris hip score. Hip range of motion was measured passively in the lying position with a goniometer and recorded in degrees according to the method suggested by the American Academy of Orthopaedic Surgeons 1988. The incidence of heterotopic ossification was 47% and the incidence of severe ossification was 11%. The severe heterotopic ossification significantly reduced clinical outcome, overall range of hip motion and certain components such as flexion, abduction and external rotation, but had no significant effect on pain, while the lower degree of ossification did not significantly influence the clinical outcome, hip motion and pain. This study has shown that only severe heterotopic ossification is of clinical significance.
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http://dx.doi.org/10.3928/01477447-20091124-13 | DOI Listing |
J Inflamm Res
January 2025
Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan, Shandong, 250014, People's Republic of China.
Background: Posttraumatic elbow stiffness is a complex complication with two characteristics of capsular contracture and heterotopic ossification. Currently, genomic mechanisms and pathogenesis of posttraumatic elbow stiffness remain inadequately understood. This study aims to identify differentially expressed genes (DEGs) and elucidate molecular networks of posttraumatic elbow stiffness, providing novel insights into disease mechanisms at transcriptome level.
View Article and Find Full Text PDFJ Rehabil Med Clin Commun
January 2025
Department of Physical and Rehabilitation Medicine, Universitair Ziekenhuis Brussel.
Background: Heterotopic ossification is a common complication after joint replacement surgery, such as hip or knee arthroplasty. In the intensive care unit, it is most commonly associated with traumatic brain injury or spinal cord injury. To prevent recurrence, surgical resection of heterotopic ossification is recommended once the ectopic bone has fully matured, which is estimated to occur after at least 12 months.
View Article and Find Full Text PDFActa Biomater
January 2025
Department of Biomedical Engineering, Lund University, Box 118, 221 00 Lund, Sweden.
While the number of studies investigating Achilles tendon pathologies has grown exponentially, more research is needed to gain a better understanding of the complex relation between its hierarchical structure, mechanical response, and failure. At the microscale, collagen fibers are, with some degree of dispersion, primarily aligned along the principal loading direction. However, during tension, rearrangements and reorientations of these fibers are believed to occur.
View Article and Find Full Text PDFJ Shoulder Elbow Surg
January 2025
Department of Orthopaedic Surgery and Rehabilitation, Loyola University Health System, Maywood, IL, USA.
Int J Surg Case Rep
December 2024
Joint Reconstruction Research Center (JRRC), Imam Khomeini Hospital, Tehran University of Medical Sciences, End of Keshavarz Blvd, 1419733141 Tehran, Iran. Electronic address:
Introduction: Heterotopic ossification (HO) is the formation of mature bone in soft tissue, often occurring after fractures and trauma. Patients with HO experience pain, joint stiffness, and other complications. Treatment aims to improve function; surgical procedures have succeeded in 83.
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