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The diagnostic performance comparison between T2 mapping and Dixon against the activity of thyroid-associated ophthalmopathy: a systematic review and meta-analysis.
Front Endocrinol (Lausanne)
December 2024
Department of Ophthalmology, The Second Affiliated Hospital of Chengdu Medical College, Nuclear Industry 416 Hospital, Chengdu, Sichuan, China.
Objective: The aim of this study was to compare the diagnostic performance of T2 mapping and Dixon in thyroid-associated ophthalmopathy's disease activity.
Methods: Published studies were collected by systematically searching the databases PubMed, Embase, Cochrane Library, Google Scholar, Medline, Web of Science, CNKI, VIP, and WANFANG. The sensitivities, specificities, likelihood ratios, and diagnostic odds ratio (DOR) were confirmed.
Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases.
Nat Genet
December 2024
Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.
Article Synopsis
Efficacy of selenium supplementation for patients with Graves' hyperthyroidism during methimazole treatment: protocol for a systematic review and meta-analysis.
BMJ Open
September 2024
Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China
Introduction: The most common cause of hyperthyroidism, Graves' disease is a common organ-specific autoimmune disease. Selenium is an essential trace element of the human body that is mainly concentrated in the thyroid gland and is involved in the synthesis and metabolism of thyroid hormones. Most studies have shown that the level of selenium is closely related to the occurrence and development of thyroid diseases, and selenium supplementation can help improve thyroid function.
View Article and Find Full Text PDFPrediction models of intravenous glucocorticoids therapy response in thyroid eye disease.
Eur Thyroid J
August 2024
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Thyroid eye disease (TED) is an autoimmune orbital disease, with intravenous glucocorticoid (IVGC) therapy as the first-line treatment. Due to uncertain response rates and possible side effects, various prediction models have been developed to predict IVGC therapy outcomes.
Methods: A thorough search was conducted in PubMed, Embase, and Web of Science databases.
Risk Factors for Recurrent Laryngeal Nerve Palsy in Thyroid Surgery: A Single Center Experience of 1147 Procedures with Intermittent Intraoperative Neuromonitoring.
J Pers Med
July 2024
School VI-School of Medicine and Health Sciences, Carl von Ossietzky Universitat Oldenburg, Ammerlander Heerstrasse 114-118, 26129 Oldenburg, Germany.
Article Synopsis
- Recurrent laryngeal nerve (RLN) palsy can occur during thyroid surgery and monitoring the nerve is crucial to minimize this risk; this study looks to identify and review both known and new factors contributing to RLN palsy.
- The research analyzed data from 1,147 patients who underwent thyroid surgery between 2016 and 2020, using logistic regression to understand the factors that increase the risk of RLN palsy.
- The findings showed that surgeries for Graves' disease, thyroid cancer, and recurrent goiter significantly increase the risk for RLN palsy, with longer surgeries also correlating to higher risk; however, factors like gender and surgeon experience did not show significant impacts.
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