Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2106/JBJS.I.00124 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The central nervous system (CNS) parenchyma has conventionally been believed to lack lymphatic vasculature, likely due to a non-permissive microenvironment that hinders the formation and growth of lymphatic endothelial cells (LECs). Recent findings of ectopic expression of LEC markers including Prospero Homeobox 1 (PROX1), a master regulator of lymphatic differentiation, and the vascular permeability marker Plasmalemma Vesicle Associated Protein (PLVAP), in certain glioblastoma and brain arteriovenous malformations (AVMs), has prompted investigation into their roles in cerebrovascular malformations, tumor environments, and blood-brain barrier (BBB) abnormalities. To explore the relationship between ectopic LEC properties and BBB disruption, we utilized endothelial cell-specific overexpression mutants.
View Article and Find Full Text PDFDistinct Clinical Presentations of Vein of Galen Aneurysmal Malformation: A Case Series.
Clin Case Rep
January 2025
Breastfeeding Research Center, Family Health Research Institute Tehran University of Medical Sciences Tehran Iran.
We present two cases of vein of Galen aneurysmal malformation, detected in early life, with differing outcomes. This suggests that early detection of this malformation in fetuses or neonates does not necessarily indicate a poor prognosis, highlighting the need for vigilant monitoring and timely intervention to optimize outcomes.
View Article and Find Full Text PDFEndoscopic third ventriculostomy for hydrocephalus accompanied by dural arteriovenous fistulae: a case report and literature review.
Acta Neurochir (Wien)
January 2025
Department of Neurosurgery, Kanazawa University, 13-1 Takara-machi, Kanazawa, 9208641, Ishikawa, Japan.
A 54-year-old man presented with gait disturbances, urinary incontinence, and headache for 6 months. Head computed tomography indicated several high-density mass lesions in the quadrigeminal cistern, causing occlusive hydrocephalus. Digital subtraction angiography confirmed tentorial dural arteriovenous fistulae (AVF).
View Article and Find Full Text PDFRenal Clear Cell Carcinoma Masquerading As Brain Arteriovenous Malformation: A Case Report and Review of the Literature.
Cureus
December 2024
Neurosurgery, Southmead Hospital, North Bristol NHS, Bristol, GBR.
Cerebral arteriovenous malformations (AVMs) are tangles of abnormal vessels with early arteriovenous (AV) shunting that can lead to intracerebral hemorrhage, seizures, neurologic deficit, or headache. To date, only a few cases of carcinomas metastasizing to pre-existing cerebral AVMs have been reported in the literature. However, renal clear cell carcinoma (RCC) brain metastases that exhibit early AV shunting, where AVM pathology is not present, are extremely rare.
View Article and Find Full Text PDFRemoval of microcatheter entrapped in the middle cerebral artery in a neonate via common carotid arteriotomy.
J Vasc Surg Cases Innov Tech
February 2025
Department of Vascular Surgery, Sir Charles Gairdner Hospital, Perth, Australia.
A 2-day-old neonate was referred to the vascular surgery service owing to concerns of limb perfusion after entrapment of a microcatheter in the middle cerebral artery. The catheter was inserted via the umbilical artery to treat a vein of Galen arteriovenous malformation. This catheter inadvertently became entrapped owing to device failure, was cut at the insertion site, and left in situ for 3 months.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!