The ability of cyanoxime-based synthons to act as versatile synthetic tools for the construction of co-crystals is demonstrated through the preparation and structural characterization of seven co-crystals. Cyanoximes can bind effectively to both five-membered and six-membered N-heterocyclic hydrogen-bond acceptors, and they also display selectivity towards the best acceptor (as determined using semi-empirical AM1 calculations) in ditopic compounds.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748950 | PMC |
| http://dx.doi.org/10.1039/b811322j | DOI Listing |
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